AIDS vaccine trial exceeds expectations

Sep 23, 2005

An experimental AIDS vaccine of Merck & Co. has exceeded expectations and led to a double enrollment in the trial to 3,000, researchers said.

The trial, conducted in healthy volunteers to determine their immune response to the vaccine, might indicate whether the immune reactions could prevent or control AIDS, reported the Wall Street Journal Friday.

The vaccine, called MRKAd5, uses an adenovirus -- a common-cold virus -- as a missile armed with man-made copies of three AIDS virus genes, has resulted in a stronger-than-expected immune response.

MRKAd5 has boosted such killer T-cells, which seek and destroy human cells infected by HIV by 50-fold to 100-fold -- an immune reaction comparable with successful vaccines for diseases like smallpox or measles, according to Lawrence Corey, principal investigator of the HIV Vaccine Trials Network in Seattle.

However, the vaccine doesn't elicit antibodies, another key element of immune protection.

Copyright 2005 by United Press International

Explore further: Everglades trail surveyed for cultural artifacts

add to favorites email to friend print save as pdf

Related Stories

MasterCard, Zwipe announce fingerprint-sensor card

7 hours ago

On Friday, MasterCard and Oslo, Norway-based Zwipe announced the launch of a contactless payment card featuring an integrated fingerprint sensor. Say goodbye to PINs. This card, they said, is the world's ...

Plastic nanoparticles also harm freshwater organisms

9 hours ago

Organisms can be negatively affected by plastic nanoparticles, not just in the seas and oceans but in freshwater bodies too. These particles slow the growth of algae, cause deformities in water fleas and impede communication ...

Atomic trigger shatters mystery of how glass deforms

9 hours ago

Throw a rock through a window made of silica glass, and the brittle, insulating oxide pane shatters. But whack a golf ball with a club made of metallic glass—a resilient conductor that looks like metal—and the glass not ...

US company sells out of Ebola toys

17 hours ago

They might look tasteless, but satisfied customers dub them cute and adorable. Ebola-themed toys have proved such a hit that one US-based company has sold out.

Recommended for you

US state reaches deal to keep dinosaur mummy

8 hours ago

North Dakota reached a $3 million deal to keep a rare fossil of a duckbilled dinosaur on display at the state's heritage center, where it will serve as a cornerstone for the facility's $51 million expansion, officials said ...

Jerusalem stone may answer Jewish revolt questions

11 hours ago

Israeli archaeologists said Tuesday they have discovered a large stone with Latin engravings that lends credence to the theory that the reason Jews revolted against Roman rule nearly 2,000 ago was because ...

Kung fu stegosaur

11 hours ago

Stegosaurs might be portrayed as lumbering plant eaters, but they were lethal fighters when necessary, according to paleontologists who have uncovered new evidence of a casualty of stegosaurian combat. The ...

User comments : 0