Vitamin C: possible cancer-killing promise

Sep 12, 2005

High-dose intravenous vitamin C may be effective in treating cancer, newly published research indicates.

Studies during the 1970s first suggested administration of high doses of ascorbate might provide a clinical benefit for treating cancer, but later studies using the same high doses found no benefit.

However, researchers now say the original studies used intravenous and oral ascorbate, while subsequent studies used only oral administration. Recognizing those differences might account for the disparate clinical outcomes, Mark Levine and colleagues at the National Institutes of Health reexamined intravenous ascorbate therapy in cultured cancer cell lines.

The researchers found ascorbate killed cancer cells at concentrations that would only be achievable through intravenous infusion. Normal cells were not affected by ascorbate at any concentration.

Additionally, the scientists report ascorbate treatment led to the formation of hydrogen peroxide, a chemical that can kill cells, suggesting a potential mechanism for the therapy.

The research appears in this week's online, early edition of the Proceedings of the National Academy of Sciences.

Copyright 2005 by United Press International

Explore further: Parents drive kids' car choices

add to favorites email to friend print save as pdf

Related Stories

Researchers evaluate new bowel prep approaches

Oct 26, 2009

While there is little doubt concerning the effectiveness of colonoscopy procedures to detect colon cancer, a new study presented at the American College of Gastroenterology's 74th Annual Scientific Meeting in San Diego places ...

Support for adjunctive vitamin C treatment in cancer

Mar 06, 2009

Serious flaws in a recent study, which concluded that high doses of vitamin C reduce the effectiveness of chemotherapeutic drugs in the treatment of cancer, are revealed in the current issue of Alternative and Complementary Th ...

Vitamin C injections slow tumor growth in mice

Aug 04, 2008

High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the National ...

Recommended for you

How the financial crisis boosted the best leaders

3 hours ago

Six years on from the financial crisis and still many of us feel deeply unsure about institutions and individuals we had previously revered as beacons of reliability and certainty. The need to repair that ...

User comments : 0