Nanoscale systems for early diagnosis

Jul 14, 2005

A partnership of scientists from the College of Engineering at UC Santa Barbara, Washington University in St. Louis and UC Berkeley have been awarded $12.5 million to develop nanoscale agents to provide early diagnosis and treatment of acute pulmonary and systemic vascular injury over the next five years. The organizations were selected as a collaborative "Program of Excellence in Nanotechnology" (PEN) by the National Heart Lung and Blood Institute of the National Institutes of Health (NIH).

The team, led at UCSB by Professor Craig Hawker, Director of the Materials Research Laboratory, and coordinated by Professor Karen Wooley at Washington University in St. Louis will use nanoscale materials as carriers for diagnostic systems and to deliver therapeutic agents. Hawker and Wooley working with Professor Jean Frechet, PhD, at the University of California, Berkeley, will be developing a way to trigger a breakdown of the nanoparticles after a payload, such as a drug or antiviral agent, is delivered directly to a diseased zone. Targeted nanoparticles will search out arteries that are under stress or are diseased.

The nanoscale designs are based on the concept that advanced nanotechnologies can help overcome inherent limitations of molecular imaging and therapeutic gene transfer.

"I think part of the reason we received this grant was due to UCSB's excellence in soft materials and in engineering," said Hawker. Acute vascular injury and inflammation have been chosen as general targets since they affect tissues broadly, including those of the lung and cardiovascular system.

Source: University of California - Santa Barbara

Explore further: How we can substitute critical raw materials in catalysis, electronics and photonics

add to favorites email to friend print save as pdf

Related Stories

Mutant bacteria that keep on growing

Feb 18, 2015

The typical Escherichia coli, the laboratory rat of microbiology, is a tiny 1-2 thousandths of a millimeter long. Now, by blocking cell division, two researchers at Concordia University in Montreal have g ...

Improving energy efficiency one atom at a time

Feb 17, 2015

Paul Simmonds looks at his molecular beam epitaxy (MBE) system the way other guys do a candy apple red Porsche. The sci-fi looking machine used to design and create new materials at the atomic level lights ...

Novel crumpling method takes flat graphene from 2D to 3D

Feb 17, 2015

Researchers at the University of Illinois at Urbana-Champaign have developed a unique single-step process to achieve three-dimensional (3D) texturing of graphene and graphite. Using a commercially available ...

'Nanogap' for early detection of bladder and kidney cancer

Feb 16, 2015

A new mobile device that allows bladder and kidney cancer to be detected at an early stage. This is being worked on by Wilfred van der Wiel, professor of nanoelectronics at the University of Twente MESA+ research institute. ...

Recommended for you

Semiconductor miniaturisation with 2D nanolattices

Feb 26, 2015

A European research project has made an important step towards the further miniaturisation of nanoelectronics, using a highly-promising new material called silicene. Its goal: to make devices of the future ...

Ultra-small block 'M' illustrates big ideas in drug delivery

Feb 26, 2015

By making what might be the world's smallest three-dimensional unofficial Block "M," University of Michigan researchers have demonstrated a nanoparticle manufacturing process capable of producing multilayered, precise shapes.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.