MU College of Veterinary Medicine to study efficacy of cancer drug in dogs

Oct 05, 2010

A cancer drug that benefits people may soon benefit man's best friend.

Kim Selting, assistant teaching professor of oncology at the MU College of Veterinary Medicine, is the principal investigator in a study that examines the efficacy of Attaxol™ in dogs with naturally occurring cancer. Attaxol was developed, and is produced, by CritiTech, a Lawrence, Kan. drug development company.

Kim Selting, assistant teaching professor of oncology at the MU College of Veterinary Medicine.

"Cancer is one of the most common causes of death in dogs," Selting said. "This study is important because most chemotherapy drugs available to people can be used in dogs, except for the highly successful taxanes that can keep cancer from proliferating throughout the body. The Attaxol formulation is built specifically for dogs and could allow taxanes to be used by veterinarians."

MU veterinarians will conduct the clinical part of the study and assess cancer response in the dogs involved in the study. Data from an earlier safety study was used to establish a starting dose, and this second study will consist of an escalation phase to determine the optimal dose, followed by an extended treatment. CritiTech scientists will analyze blood samples to determine plasma levels of the drug during the course of treatment. Enrollment of in the study is set to start in mid October, and it is anticipated that the study will take about two years to complete.

The Scott Endowed Program in Veterinary Oncology at MU is one of the largest veterinary programs in the country and actively initiates and participates in clinical trials, as well as provides routine treatment of animals with cancer, including chemotherapy, cancer surgery and radiation therapy.

"We are excited about our continued collaboration with the University of Missouri College of Veterinary Medicine and the commercial opportunity to use CritiTech's fine-particle drug technology in the veterinary field," said Sam Campbell, CritiTech president and chairman.

Explore further: Video: Researchers instruct scientists in giant role tiny fungi play

add to favorites email to friend print save as pdf

Related Stories

Dogs carrying hospital superbug

May 31, 2007

Veterinarians in Sweden say dogs may be spreading the MRSA superbug in veterinary clinics. The first Swedish case of a dog contracting the virus was recorded at a clinic in Stockholm last fall, The Local newspaper said Wednesday.

Recommended for you

The ABC's of animal speech: Not so random after all

1 hour ago

The calls of many animals, from whales to wolves, might contain more language-like structure than previously thought, according to study that raises new questions about the evolutionary origins of human language.

Manatees could lose their endangered species status

11 hours ago

About 2,500 manatees have perished in Florida over the last four years, heightening tension between conservationists and property owners as federal officials prepare to decide whether to down-list the creature to threatened ...

User comments : 0