Low socioeconomic status linked with more severe colorectal cancer

Oct 02, 2010

People living in economically deprived neighborhoods were more likely to be diagnosed with late-stage, non-localized colorectal cancer, even after researchers controlled for known colorectal cancer risk factors, according to data presented at the Third American Association for Cancer Research Conference on The Science of Cancer Health Disparities, being held Sept. 30-Oct. 3, 2010.

"Community clinical practitioners should be encouraged to understand the neighborhood characteristics of their patients and use that information to guide their encounters with patients, to help reduce disparities for colorectal , which is a preventable disease," said study author Chyke Doubeni, M.D., M.P.H., assistant professor of family medicine and community health at the University of Massachusetts Medical School.

Researchers evaluated data from the NIH-AARP Diet and Health Study, a prospective cohort of participants from six U.S. states and two metropolitan areas. Data were obtained from 1995 to 2003, and none of the participants had a history of colorectal cancer.

Socioeconomic status was based on an empirically derived neighborhood socioeconomic deprivation index from 2000 U.S. census data.

Findings revealed 6,934 cases of colorectal cancer among 560,288 eligible participants; 59 percent of these cases were non-localized, defined as regional, distant or unstaged tumors. After adjusting for age and sex, the researchers reported a colorectal of 17.5 per 10,000 person-years.

Those participants who resided in the least socioeconomically deprived neighborhoods had an incidence rate of 16.2 percent compared with 19.8 percent for those living in the most disadvantaged neighborhoods.

After further accounting for individual-level education, associated with the risk for colorectal cancer, history of smoking and , findings revealed that those in the most deprived neighborhoods had a 13 percent higher overall incidence of colorectal cancer and 15 percent higher incidence of non-localized colorectal cancer compared with those in the least deprived neighborhoods.

Doubeni and colleagues plan to evaluate potential differences between men and women and to evaluate underlying reasons for disparities, including failures along the continuum of care and health care utilization histories.

"We need to understand more about the health care utilization patterns of patients in poorer neighborhoods and obstacles to colorectal cancer screening in those neighborhoods," Doubeni said.

Explore further: AstraZeneca cancer drug, companion test approved

add to favorites email to friend print save as pdf

Related Stories

Family history and screening for colorectal cancer

Jun 09, 2008

A new study indicates that African Americans with a family history of colorectal cancer are less likely to be screened than African Americans at average risk for the disease. There is also some evidence to indicate that AA ...

Recommended for you

Putting the brakes on cancer

Dec 19, 2014

A study led by the University of Dundee, in collaboration with researchers at our University, has uncovered an important role played by a tumour suppressor gene, helping scientists to better understand how ...

Peanut component linked to cancer spread

Dec 19, 2014

Scientists at the University of Liverpool have found that a component of peanuts could encourage the spread and survival of cancer cells in the body.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.