Link established between erectile dysfunction and calcified coronary arteries

Jun 01, 2010

In the largest study to date evaluating erectile dysfunction (ED) and coronary artery calcification, researchers at Mount Sinai School of Medicine have determined that men with ED are at a significantly increased risk of high coronary artery calcification scores (CACS), a known predictor of future cardiovascular events. The research was presented this week at the American Urological Association (AUA) meeting in San Francisco.

The study, titled "Erectile Dysfunction is an Independent Risk Factor for the Presence of High Risk Coronary Artery Calcification," evaluated 1,119 men enrolled in the World Trade Center Medical Monitoring and Treatment Program, 327 of which had ED. The researchers learned that after adjusting for comorbidities men with ED had a 54 percent greater likelihood of having a high-risk CACS than men without ED. The increased risk was similar to that of patients with a history of hypertension and smoking.

"Our data further solidify the concept that ED is a harbinger-indicator of current and future cardiovascular disease," said Natan Bar-Chama, MD, Director of Male Reproductive Medicine and Surgery and associate professor of urology at Mount Sinai School of Medicine. "These data show an indisputable connection between ED and ."

The mean age of the men in the study was 50.5 years. All patients were evaluated with a cardiac to determine CACS. was assessed using a validated questionnaire and defined as a Sexual Health Inventory for Men (SHIM) score of less than 22. After adjusting for risk factors like diabetes, smoking, and body-mass index, Dr. Bar-Chama's team determined that ED was independently associated with a 54 percent increased risk of CACS.

"The finding certainly raises the question as to what diagnostic tests we should perform in the newly diagnosed ED patient in order to assess cardiovascular risk," he added. "For example, should we be recommending that CACS scores be obtained in all these patients? Also, should we routinely be measuring serum inflammatory markers, conducting assessment of endothelial function or cardiac stress testing? Guidelines are urgently needed to stratify cardiovascular risk in the newly diagnosed ED patient in light of the significant and clear association between ED and cardiovascular disease."

Explore further: Recorded Ebola deaths top 7,000

Provided by The Mount Sinai Hospital

5 /5 (1 vote)
add to favorites email to friend print save as pdf

Related Stories

Erectile dysfunction influenced by race and ethnicity

Jan 31, 2007

According to a new study in The Journal of Sexual Medicine, erectile dysfunction (ED) is highly prevalent across white, black and Hispanic populations in the United States. For the first time in an adequately-sized, nation ...

Prevent smoking to reduce risk of erectile dysfunction

Jul 27, 2007

Men who smoke cigarettes run an increased risk of experiencing erectile dysfunction, and the more cigarettes smoked, the greater the risk, according to a study by Tulane University researchers published in the American Journal ...

Recommended for you

Recorded Ebola deaths top 7,000

21 hours ago

The worst Ebola outbreak on record has now killed more than 7,000 people, with many of the latest deaths reported in Sierra Leone, the World Health Organization said as United Nations Secretary-General Ban ...

Liberia holds Senate vote amid Ebola fears (Update)

Dec 20, 2014

Health workers manned polling stations across Liberia on Saturday as voters cast their ballots in a twice-delayed Senate election that has been criticized for its potential to spread the deadly Ebola disease.

Evidence-based recs issued for systemic care in psoriasis

Dec 19, 2014

(HealthDay)—For appropriately selected patients with psoriasis, combining biologics with other systemic treatments, including phototherapy, oral medications, or other biologic, may result in greater efficacy ...

Bacteria in caramel apples kills at least four in US

Dec 19, 2014

A listeria outbreak believed to originate from commercially packaged caramel apples has killed at least four people in the United States and sickened 28 people since November, officials said Friday.

Steroid-based treatment may answer needs of pediatric EoE patients

Dec 19, 2014

A new formulation of oral budesonide suspension, a steroid-based treatment, is safe and effective in treating pediatric patients with eosinophilic esophagitis (EoE), according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.