Researchers demonstrate that 'safe' cigarettes are as hazardous as tobacco

May 12, 2010

Using the same technique they developed to document the harmful effects of tobacco products, a team of researchers found that cigarettes made without tobacco or nicotine may be more carcinogenic because they actually induce more extensive DNA damage than tobacco products. The technique has been awarded U.S. patent No. 7,662,565.

The research team was led by Zbigniew Darzynkiewicz, M.D., Ph.D., professor of pathology. Their study, "DNA damage response induced by exposure of human lung adenocarcinoma cells to smoke from tobacco- and nicotine-free cigarettes," will appear in the June 1 issue of Cell Cycle (Volume 9, Issue 11).

Using laser scanning cytometry (LSC) technology to measure DNA damage response to the smoke from commercially available tobacco- and nicotine-free cigarettes, the research team expected to find the alternative products were less hazardous than regular tobacco cigarettes. However, their data suggest that exposure of cells to smoke from tobacco- and nicotine-free cigarettes leads to formation of double-strand DNA breaks (DSBs). Since DSBs are potentially carcinogenic, the data indicate that smoking tobacco- and nicotine-free cigarettes is at least as hazardous as those containing tobacco and .

The authors conclude that their methodology to assess the potential carcinogenic properties of , based on measurement of DNA damage response as assessed by LSC, provides a useful addition to the battery of genotoxic tests for probing hazards. Such tests, which can be applied to evaluate the effects of cigarettes and cigarette surrogate products on human health, can be important tools for regulatory agencies such as the or, in the case of environmental smoke, by the .

Explore further: Pollutants from coal-burning stoves strongly associated with miscarriages in Mongolia

Provided by New York Medical College

not rated yet
add to favorites email to friend print save as pdf

Related Stories

Smokers at risk from their own 'second-hand' smoke

Jan 29, 2010

It is well known that smokers damage their health by directly inhaling cigarette smoke. Now, research published in BioMed Central's open access journal Environmental Health has shown that they are at additional risk from b ...

Rodent smoke screen

Dec 08, 2009

Rats passively exposed to tobacco smoke become dependent on nicotine, according to a new study by Dr. Adrie Bruijnzeel and colleagues from the University of Florida in the US. Their findings of how rats' brains respond to ...

Growing evidence of marijuana smoke's potential dangers

Aug 05, 2009

In a finding that challenges the increasingly popular belief that smoking marijuana is less harmful to health than smoking tobacco, researchers in Canada are reporting that smoking marijuana, like smoking ...

Recommended for you

Rising role seen for health education specialists

59 minutes ago

(HealthDay)—A health education specialist can help family practices implement quality improvement projects with limited additional financial resources, according to an article published in the March/April ...

FDA proposes first regulations for e-cigarettes

1 hour ago

The federal government wants to prohibit sales of electronic cigarettes to minors and require approval for new products and health warning labels under regulations being proposed by the Food and Drug Administration.

Vermont moves toward labeling of GMO foods

1 hour ago

Vermont lawmakers have passed the country's first state bill to require the labeling of genetically modified foods as such, setting up a war between the behemoth U.S. food industry and an American public that overwhelmingly ...

User comments : 3

Adjust slider to filter visible comments by rank

Display comments: newest first

tpb
not rated yet May 12, 2010
Smokeless cigarettes have nicotine and glycerin in them.
The glycerin is to make a smoke like visible vapor.
If the nicotine produces genetic damage, we better stop using nicotine patches, unless the claim is that glycerin causes genetic damage.
dysterbed
not rated yet May 12, 2010
I think this article is still referring to combustible products like Smoke-Free that use other plant materials than tobacco(coffee bean husks are popular I believe). I don't believe they are talking about the E-Cig vaporizers, which don't actually combust any plant materials. I still think it is the ash and tar that cause most of the problems, genetically or otherwise.
neiorah
not rated yet May 13, 2010
What about the devices that just use a vapor of nicotine and contain no tar or smoke? Are these any safer?

More news stories

Rising role seen for health education specialists

(HealthDay)—A health education specialist can help family practices implement quality improvement projects with limited additional financial resources, according to an article published in the March/April ...

FDA proposes first regulations for e-cigarettes

The federal government wants to prohibit sales of electronic cigarettes to minors and require approval for new products and health warning labels under regulations being proposed by the Food and Drug Administration.

When things get glassy, molecules go fractal

Colorful church windows, beads on a necklace and many of our favorite plastics share something in common—they all belong to a state of matter known as glasses. School children learn the difference between ...

FCC to propose pay-for-priority Internet standards

The Federal Communications Commission is set to propose new open Internet rules that would allow content companies to pay for faster delivery over the so-called "last mile" connection to people's homes.

SK Hynix posts Q1 surge in net profit

South Korea's SK Hynix Inc said Thursday its first-quarter net profit surged nearly 350 percent from the previous year on a spike in sales of PC memory chips.

Brazil enacts Internet 'Bill of Rights'

Brazil's president signed into law on Wednesday a "Bill of Rights" for the digital age that aims to protect online privacy and promote the Internet as a public utility by barring telecommunications companies ...