Which treatment is effective in maintaining remission in ulcerative colitis: Probiotic or placebo?

Apr 19, 2010

A research team from China compared the therapeutic effects of probiotics treatment and non-probiotics treatment on ulcerative colitis in remission induction and maintenance. The meta-analysis showed that probiotic treatment was more effective than placebo in maintaining remission in ulcerative colitis.

Inflammatory bowel disease is a chronic recurrent disease, which mainly consists of ulcerative colitis and Crohn's disease, and whose causes are as yet unclear. Many clinical and research studies have indicated that intestinal flora dysbacteriosis contributes to the pathogenesis of ulcerative colitis.

Probiotics are non-pathogenic beneficial flora, which have important effects on maintaining the balance of intestinal flora. Many studies have discussed the positive effects of probiotics for treating stomach and intestine diseases, including ulcerative colitis. However, the sample size has been relatively small, such that there is no definitive evidence as to whether probiotics are helpful.

A research team from China systematically evaluated probiotics' curative effects for treating ulcerative colitis based on existing random control trials. Their study will be published on April 21, 2010 in the .

Through meta-analysis, they concluded that probiotics should be considered as an auxiliary medicine in the remission induction stage and maintenance stage of .

Explore further: NY and NJ say they will require Ebola quarantines

More information: Sang LX, Chang B, Zhang WL, Wu XM, Li XH, Jiang M. Remission induction and maintenance effect of probiotics on ulcerative colitis: A meta-analysis. World J Gastroenterol 2010;16(15): 1908-1915. www.wjgnet.com/1007-9327/full/v16/i15/1908.htm

add to favorites email to friend print save as pdf

Related Stories

Research team identifies genes linked to ulcerative colitis

Mar 17, 2010

A study of the human genome led by Cedars-Sinai researchers has now identified genes linked to ulcerative colitis, offering clues as to what causes the condition and potential avenues for new therapies to treat the disease.

Predictors of ulcerative colitis severity

Jan 19, 2010

Ulcerative colitis (UC) is a chronic disease involving the large intestine which causes inflammation along with local and systemic symptoms. It affects individuals worldwide, with a higher prevalence in Canada. The course ...

Blueberries counteract intestinal diseases

Feb 09, 2010

It is already known that blueberries are rich in antioxidants and vitamins. New research from the Lund University Faculty of Engineering in Sweden shows that blueberry fibre are important and can alleviate and protect against ...

Promising probiotic treatment for inflammatory bowel disease

Jan 20, 2010

Bacteria that produce compounds to reduce inflammation and strengthen host defences could be used to treat inflammatory bowel disease (IBD). Such probiotic microbes could be the most successful treatment for IBD to date, ...

Recommended for you

NY and NJ say they will require Ebola quarantines

11 hours ago

The governors of New Jersey and New York on Friday ordered a mandatory, 21-day quarantine for all doctors and other arriving travelers who have had contact with Ebola victims in West Africa.

WHO: Mali case may have infected many people

15 hours ago

The World Health Organization says a toddler who brought Ebola to Mali was bleeding from her nose during her journey on public transport and may have infected many people.

Two US nurses are declared cured of Ebola

16 hours ago

Two American nurses were declared cured of Ebola on Friday, and one was healthy enough to leave the hospital and meet President Barack Obama for a hug.

User comments : 0