Supplement your stem cells

Apr 07, 2010

A nutritional supplement could stimulate the production of stem cells integral for repairing the body. Research published in BioMed Central's open access Journal of Translational Medicine suggests that a commercially-available supplement can increase the blood circulation of hematopoietic stem cells, which can give rise to all blood cells, and endothelial progenitor cells, which repair damage to blood vessels.

Thomas E. Ichim from Medistem Incorporated, USA worked with a team of 13 researchers from industry and academia to further investigate whether this supplement, containing a cocktail of green tea, astralagus, goji berry extracts, 'good' bacteria Lactobacillus fermentum, antioxidant ellagic acid, immune enhancer beta 1,3 glucan and vitamin D3, was able to increase the number of stem cells circulating in the . They recruited 18 healthy adults aged between 20 and 72 who stopped any other 4-5 days before starting a two-week course of this supplement, taking it twice daily.

The researchers took blood from the participants before they started the course and on days 1, 2, 7 and 14 to test for signs of stem cell activity by looking for cells expressing the genetic stem cell markers CD133, CD34 and KDR. They then confirmed whether taking the supplement changed the overall levels of hematopoietic stem cells and endothelial progenitor cells in the blood by using HALO (Hematopoietic Assay via Luminescent Output) and colony forming assays respectively.

Hematopoietic stem cells and endothelial progenitor cells increased after taking the nutritional supplement, suggesting that the supplement may be a useful stimulator for both types of stem cells. In this study, the levels of these stem cells peaked at 2-7 days and started to drop at 14 days, suggesting that this supplement could be used for continuous treatment for conditions associated with decreases in these stem cells such as Alzheimer's Disease. Other therapeutic treatments used to recruit are not viable as long-term solutions due to costs and increased health risks caused by the extremely high levels of that these treatments maintain in the blood.

"To our knowledge, this is the first study demonstrating profound mobilization effect with possible clinical significance by a food supplement-based approach", say the authors, adding, "Indeed it may be possible that our supplement could be beneficial in conditions associated with reduced such as diabetes or in smokers which possess lower baseline values as compared to controls". Although they are quick to add, "However, given commercial pressures associated with this largely unregulated field, we propose detailed scientific investigations must be made before disease-associated claims are made by the scientific community".

Explore further: Growing a blood vessel in a week

More information: Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects, Nina A Mikirova, James A Jackson, Ron Hunninghake, Julian Kenyon, Kyle WH Chan, Cathy A Swindlehurst, Boris Minev, Amit N Patel, Michael P Murphy, Leonard Smith, Famela Ramos, Doru T Alexandrescu, Thomas E Ichim and Neil H Riordan, Journal of Translational Medicine (in press), www.translational-medicine.com/

add to favorites email to friend print save as pdf

Related Stories

Theory of single stem cell for blood components challenged

Mar 04, 2010

Components of the blood or hematopoietic system derive from stem cell subtypes rather than one single stem cell that gives rise to all the different kinds of blood cells equally, said scientists from Baylor College of Medicine ...

Italians report stem-cell advances

Sep 06, 2006

Italian scientists have reportedly made important advances in stem-cell research, specifically for kidney and liver disease.

Recommended for you

Growing a blood vessel in a week

Oct 24, 2014

The technology for creating new tissues from stem cells has taken a giant leap forward. Three tablespoons of blood are all that is needed to grow a brand new blood vessel in just seven days. This is shown ...

Testing time for stem cells

Oct 24, 2014

DefiniGEN is one of the first commercial opportunities to arise from Cambridge's expertise in stem cell research. Here, we look at some of the fundamental research that enables it to supply liver and pancreatic ...

Team finds key signaling pathway in cause of preeclampsia

Oct 23, 2014

A team of researchers led by a Wayne State University School of Medicine associate professor of obstetrics and gynecology has published findings that provide novel insight into the cause of preeclampsia, the leading cause ...

Rapid test to diagnose severe sepsis

Oct 23, 2014

A new test, developed by University of British Columbia researchers, could help physicians predict within an hour if a patient will develop severe sepsis so they can begin treatment immediately.

User comments : 1

Adjust slider to filter visible comments by rank

Display comments: newest first

drprasher
not rated yet Apr 11, 2010
Natural methods to rejuvenate & regenerate the abbretions in various cells due to any chronic disease / ageing.
Rejuvenation, The Panchakarma therapeutic techniques and Traditional treatments that were used by kings-queens & allied persons in Olden Days are the most powerful methods to utilize the nutrients available within the body systems, to preserve physical-vital-energy and to save the body from decay & rejuvenation as well. Latest scientific research has confirmed findings of stem cells at the routes/systems that are touched/ reactivated following the Panchakarma technique.