Cooling inflammation for healthier arteries

Feb 16, 2010

Agricultural Research Service (ARS)-funded scientists have reported new reasons for choosing "heart-healthy" oats at the grocery store.

Nutritionist Mohsen Meydani, director of the Vascular Biology Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in Boston, Mass., led the research on the oat compounds, called avenanthramides. Meydani previously has shown that phenolic in oats obstruct the ability of to stick to artery walls.

inside the arterial wall is part of the process that eventually leads to a disorder known as atherosclerosis. Meydani and colleagues have reported findings that suggest the avenanthramides of oats decrease the expression of inflammatory . The study showed that forms of avenanthramides possess potential anti-inflammatory properties through inhibiting factors that are linked with activating proinflammatory cytokines.

Cytokines are small proteins released by cells while seeking to protect and repair tissue. Some trigger inflammation, for example, while responding to infection. Inhibiting inflammation through diet, drugs, or key nutrients is considered to be of great benefit in preventing atherosclerosis. Details of this study can be found in the scientific journal Free Radical Biology & Medicine.

The study provides additional indications of the potential health benefit of oat consumption in the prevention of coronary heart disease beyond its known effect through lowering blood cholesterol.

Explore further: Were clinical trial practices in East Germany questionable?

More information: Read more about this research in the February 2010 issue of Agricultural Research magazine, available online at: www.ars.usda.gov/is/AR/archive/feb10/cell0210.htm .

Provided by United States Department of Agriculture

5 /5 (1 vote)
add to favorites email to friend print save as pdf

Related Stories

Studies provide insight into key oat chemical

Feb 01, 2010

Studies conducted by Agricultural Research Service (ARS) scientists are helping to increase understanding about the environmental factors that regulate production of avenanthramides (Avns), metabolites with potent antioxidant ...

Two drugs may stabilize plaques in atherosclerosis

Nov 13, 2006

Two drugs that a Wake Forest University School of Medicine research team has been investigating for lupus for several years may stabilize atherosclerotic plaque in the walls of arteries and help avert heart attacks and strokes. ...

Zinc may reduce pneumonia risk in nursing home elderly

Oct 22, 2007

When elderly nursing home residents contract pneumonia, it is a blow to their already fragile health. Simin Nikbin Meydani, DVM, PhD of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University and ...

New insights into chronic inflammation and atherosclerosis

May 25, 2007

[B]Inflammatory rheumatic disease and smoking independently predict aortic inflammation, suggests study of coronary artery surgery survivors[/B] Rheumatoid arthritis, lupus, and other inflammatory rheumatic diseases are ...

Failure to bridle inflammation spurs atherosclerosis

Jun 18, 2008

When a person develops a sore or a boil, it erupts, drawing to it immune system cells that fight the infection. Then it resolves and flattens into the skin, often leaving behind a mark or a scar.

Recommended for you

Were clinical trial practices in East Germany questionable?

Oct 23, 2014

Clinical trials carried out in the former East Germany in the second half of the 20th century were not always with the full knowledge or understanding of participants with some questionable practices taking place, according ...

Schumacher's doctor sees progress after injury

Oct 23, 2014

A French physician who treated Michael Schumacher for nearly six months after the Formula One champion struck his head in a ski accident says he is no longer in a coma and predicted a possible recovery within three years.

User comments : 0