Research Shows Overweight Patients More Challenging to Sedate

Oct 16, 2009
Deepak Krishnan, DDS

(PhysOrg.com) -- Patients with higher body mass indexes are more challenging to sedate, according to results found by a University of Cincinnati (UC) researcher studying data from common oral surgeries.

Karen Potaczek, DDS, chief resident at UC Health division of oral and maxillofacial surgery, wants doctors to better understand how the increasing prevalence of obesity will affect deep sedation during surgery. To do so, she worked with Deepak Krishnan, DDS, and division chief Robert Marciani, DMD, to review data from 431 patients who had undergone intravenous sedation at the division’s clinic from December 2008 to April 2009.

They compared data on height, weight, age, gender and the reported levels of patient sedation, cooperation, discomfort and frequency of respiratory events, or obstruction of the airway.

What they found was that obese patients were more than twice as likely to require airway intervention by physicians, who had to pull their tongue forward, move their jaw or take other measures to assure the patient’s safe breathing. Those patients with higher BMIs also showed more signs of being less sedated, such as being more agitated, restless and anxious.

“Patients who are overweight or obese are more challenging to sedate and require more frequent interruptions in the surgery for repositioning and management of their airway,” says Potaczek. “Those patients showed they were more agitated, anxious or restless. They still received similar medications as those with normal BMI, but they weren’t as sedated by those medications.”

Potaczek will present her findings Oct. 16 at the meeting of the American Association of Oral and Maxillofacial Surgeons (AAOMS) in Toronto.

She says it’s a “public health concern” for doctors to understand the effects of higher BMIs on surgical management of patients.

“A lot of surgeons elect to have these patients done in an operating room, where they are intubated,” she says. “But as obesity prevalence increases, are we going to be taking all these patients into the operating room? The outpatient oral and maxillofacial surgical setting will be significantly affected by this.”

Krishnan says the research can serve as a precautionary tool for surgeons: “When you have someone with a higher BMI, you need to make sure the anesthesia is measured more carefully. It’s a very thin balance between a patient being more sedated and being dangerously sedated.”

He says the division will conduct future studies to look at the effects of different anesthetics on overweight or .

Krishnan also will present at the AAOMS conference, speaking about the complications of a metal condylar prostheses in patients needing reconstruction of the temporomandibular joint (TMJ).

The prostheses are used in rare cases of patients who have had facial tumors removed or trauma to the jaw joint.

Krishnan says the prostheses are manufactured as temporary devices, recommended to be replaced after one to two years by a graft or a total TMJ prosthetic. But it’s often hard to persuade patients to have a second surgery to replace the device, he says, especially when they are experiencing no side effects.

Prompted by a patient whose prostheses had eroded through the skull, Krishnan worked with researchers at Canada’s Dalhousie University to review 21 prostheses that were placed or followed by the university.

He found a 19 percent complication rate in patients, most resulting from the prosthesis moving into the skull—the largest in the literature to date.

“There have been an overwhelming number of reports that say you can leave the prostheses there, but in a smaller case review I have four of them going into the skull,” he says. “This is very concerning.”

Krishnan recommends that physicians either change out the prostheses sooner or keep a close eye on patients who want to leave them in longer than the recommended time.

Provided by University of Cincinnati (news : web)

Explore further: Early use of tracheostomy for mechanically ventilated patients not associated with improved survival

add to favorites email to friend print save as pdf

Related Stories

How often do hip and knee replacements need revision?

Sep 02, 2008

A comprehensive study using nationwide data on hip and knee replacements in England has found that one in seventy-five patients require a revision of their joint replacement after three years. Although this compares favourably ...

More pounds equals worse asthma?

May 22, 2007

A new study presented at the American Thoracic Society 2007 International Conference finds that obese people are significantly more likely to have persistent or severe persistent asthma than their thinner counterparts.

Recommended for you

People on higher incomes are happier with new knees

12 hours ago

Knee replacement surgery is a very common procedure. However, it does not always resolve function or pain in all the recipients of new knees. A study by Robert Barrack, MD and his colleagues from the Washington University ...

New search engine finds rare diagnoses

13 hours ago

Doctors are trained to think "common disease" when they meet patients in their practices, and as they rarely or never meet a rare disease, it often takes many years to reach the right diagnosis. A new search tool called FindZebra ...

User comments : 0

More news stories

If you can remember it, you can remember it wrong

(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...

B vitamins could delay dementia

(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. ...

Reducing caloric intake delays nerve cell loss

Activating an enzyme known to play a role in the anti-aging benefits of calorie restriction delays the loss of brain cells and preserves cognitive function in mice, according to a study published in the May ...

Encouraging signs for bee biodiversity

Declines in the biodiversity of pollinating insects and wild plants have slowed in recent years, according to a new study. Researchers led by the University of Leeds and the Naturalis Biodiversity Centre in the Netherlands ...

New method for producing clean hydrogen

Duke University engineers have developed a novel method for producing clean hydrogen, which could prove essential to weaning society off of fossil fuels and their environmental implications.