Researcher studies monkeys in Africa to better understand virus evolution

Oct 07, 2009 by Tania Banak

( -- Despite the importance of AIDS in human health, scientists still know very little about the diversity and ecology of AIDS-like viruses in nature.

Despite the importance of AIDS in human health, scientists still know very little about the diversity and ecology of AIDS-like viruses in nature.

To help fill that knowledge gap, a researcher at the University of Wisconsin-Madison is trying to gather information from an endangered species of monkeys in Africa before this resource is lost to habitat destruction or disease.

In a paper published in the November issue of the , Tony Goldberg, a veterinarian and epidemiologist at the UW-Madison School of Veterinary Medicine, notes the discovery of three new retroviruses in Ugandan red colobus monkeys. Retroviruses are viruses that are similar to the HIV (human immunodeficiency ).

"We didn't expect to find viruses that were so different," Goldberg says. "These are extremely different from what we've seen before in other primates, even in other red colobus."

Initially, he and his colleagues simply intended to document what viruses currently exist in red colobus monkeys in Uganda. They wanted to compare viruses from monkeys in east Africa to those in monkeys from west Africa.

Upon finding the new viruses, they asked Nelson Ting at the University of Iowa to compare the genetics of red colobus monkeys from western and eastern .

"He found 4.5 million years of separation between the two geographically separated primate groups," Goldberg says. "This is a very big difference, and it may mean that the evolution of the viruses is linked to the evolution of the monkey host — an example of 'host-virus co-evolution.'"

Their work is part of a global effort to discover new viruses. As humans encroach on wildlife habitats, such as the Ugandan forests where these live, the potential for cross-species transmission increases. There is also the risk of , and the loss of valuable information about the microbes that these endangered species harbor.

"We are still discovering new pathogens out there that may have zoonotic potential," Goldberg notes.

He continues to explore how the disturbance of primate habitat (deforestation, forest fragmentation, etc) alters the rate of infectious disease transmission. His goal is to find keys to preventing future epidemics and protect human and animal health, and also protect the environments that people and wildlife share.

Collaborators on the project include the Centers for Disease Control in Atlanta and the Global Viral Forecasting Initiative in San Francisco.

Provided by University of Wisconsin-Madison (news : web)

Explore further: Research informs HIV treatment policy for inmates

Related Stories

Viruses Can Jump Between Primates and Humans

Aug 24, 2006

Viruses that jump the species barrier between monkeys and humans can harm both people and animals, and we should take steps to reduce the risk of virus transmission. That's the message running through the September issue ...

AIDS resistance secret may be in blood

Feb 12, 2007

U.S. scientists say the absence of a specific marker in the blood and tissues of certain monkeys might be part of the key to understanding AIDS resistance.

Recommended for you

Obese British man in court fight for surgery

Jul 11, 2011

A British man weighing 22 stone (139 kilograms, 306 pounds) launched a court appeal Monday against a decision to refuse him state-funded obesity surgery because he is not fat enough.

2008 crisis spurred rise in suicides in Europe

Jul 08, 2011

The financial crisis that began to hit Europe in mid-2008 reversed a steady, years-long fall in suicides among people of working age, according to a letter published on Friday by The Lancet.

New food labels dished up to keep Europe healthy

Jul 06, 2011

A groundbreaking deal on compulsory new food labels Wednesday is set to give Europeans clear information on the nutritional and energy content of products, as well as country of origin.

Overweight men have poorer sperm count

Jul 04, 2011

Overweight or obese men, like their female counterparts, have a lower chance of becoming a parent, according to a comparison of sperm quality presented at a European fertility meeting Monday.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.