Asthma: Epidemiology, etiology and risk factors

Sep 14, 2009

An article http://www.cmaj.ca/press/cmaj080612.pdf on the epidemiology, cause and risk factors of asthma is the first in a special report on asthma in CMAJ (Canadian Medical Association Journal) designed for clinical practitioners. This review looks at risk factors for persistent asthma at different ages, including prenatal, infancy, childhood and adulthood.

Genetics, environment and host characteristics are risk factors for asthma. The significant increases in the incidence of asthma and geographic variation in prevalence rates support the idea that the environment plays a large role in the current asthma epidemic. As well, environmental triggers may affect asthma differently during various life stages and risk factors may change over time.

The report comes from the researchers conducting the Canadian Healthy Infant Longitudinal Development (CHILD) Study, a multicentre Canadian study involving 5000 pregnant women with the aim of better understanding the development of allergy and asthma in children.

"While many cross-sectional studies confirm a true increase in incidence and prevalence of asthma over the last 2-3 decades, much remains unknown as to the fundamental immune, genetic and environmental mechanisms underlying its development, and its increased expression especially in the developed world," write Dr. Malcolm Sears from McMaster University, Dr. Padmaja Subbarao, The Hospital for Sick Children (SickKids) and coauthors.

Reduction in risk of asthma, as well as true prevention, is a key but elusive goal of management.

Source: (news : web)

Explore further: UN Ebola victim leaves France after recovery

add to favorites email to friend print save as pdf

Related Stories

Asthma risk increases in children treated for HIV

Jul 01, 2008

Children whose immune systems rebound after treatment with potent anti-viral drugs for HIV infection face an increased risk of developing asthma, said a federally funded consortium of researchers led by those from Baylor ...

Cigarette use may explain asthma epidemic in children

May 21, 2007

The rise in cigarette use by adults over the past century may explain the asthma epidemic in children according to a study by researchers at the Mailman School of Public Health. The study is published this month in Annals of ...

Recommended for you

Liberia free of Ebola by Christmas, says president

2 hours ago

Liberia's president on Monday urged her countrymen to double their efforts to reach the government's goal of having zero new Ebola cases by Dec. 25, a target some experts have described as highly ambitious.

Madagascar working to contain plague outbreak

2 hours ago

Madagascar said Monday it is trying to contain an outbreak of plague—similar to the Black Death that swept Medieval Europe—that has killed 40 people and is spreading to the capital Antananarivo.

Developing a noninvasive test for endometriosis

2 hours ago

Researchers at UC San Francisco have identified patterns of genetic activity that can be used to diagnose endometriosis and its severity, a finding that may offer millions of women an alternative to surgery through a simple ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.