Embryonic stem cells used to regenerate hair on mice in Japan

Apr 20, 2009 The Yomiuri Shimbun

A university lecturer in Japan has succeeded in regenerating hair on mice using embryonic stem cells, an achievement that could pave the way for the development of treatments for conditions including hair loss, it has been learned.

Details of the breakthrough, by Mariko Yamaki of Matsumoto Dental University, will be published in the May edition of The Japanese Society for Regenerative Medicine magazine.

The work involved taking and combining them with mesenchymal stem cells _ multipotent stem cells that develop into various organs of the body -- to regenerate . Yamaki said it would be difficult to regenerate hair using only .

Yamaki extracted mesenchymal stem cells taken from the teeth of mice embryos and mixed them with mice embryonic stem cells, which form the basis of skin cells. The clumps resulting from the mix were then nurtured.

It was later found that about 40 percent of the 48 clumps had one or two hairs growing from them. When protein, which quickens growth, is added, the hair growth rate increased to about 60 percent, Yamaki said.

Hair growth was observed on all 12 that had the clumps implanted on their back muscles.

Hair papilaries, which supply nourishment to the hair, also were found to have formed on the back muscle.

"If embryonic stem cells are combined with mesenchymal stem cells, which perform a number of other functions, a different organ can probably be created," Yamaki said. "The first thing I want to try to do is regenerate hair using human embryonic stem cells."

___

(c) 2009, The Yomiuri Shimbun.
Visit the Daily Yomiuri Online at www.yomiuri.co.jp/index-e.htm/
Distributed by McClatchy-Tribune Information Services.

Explore further: Treatment for overactive bladder and irritable bowel syndrome advanced through pioneering research

add to favorites email to friend print save as pdf

Related Stories

Rat hair cells found to be true stem cells

Oct 04, 2005

Cells inside hair follicles are stem cells able to develop into the cell types needed for hair growth and follicle replacement, Swiss researchers claim.

Study: Skin cells turned into stem cells

Aug 22, 2005

The controversy over embryonic stem cell research may become moot with a procedure that turns skin cells into what appear to be embryonic stem cells.

Recommended for you

Biologists reprogram skin cells to mimic rare disease

10 hours ago

Johns Hopkins stem cell biologists have found a way to reprogram a patient's skin cells into cells that mimic and display many biological features of a rare genetic disorder called familial dysautonomia. ...

Student seeks to improve pneumonia vaccines

Aug 20, 2014

Almost a million Americans fall ill with pneumonia each year. Nearly half of these cases require hospitalization, and 5-7 percent are fatal. Current vaccines provide protection against some strains of the ...

User comments : 1

Adjust slider to filter visible comments by rank

Display comments: newest first

zevkirsh
not rated yet Apr 20, 2009
i am not only the president of the embryonic folicular growth club for men, but i am a member.
bring it on science!