Surgical gel used to stop bleeding could confuse mammograms

Apr 14, 2009

Dr. Kathleen Ward noticed something odd when she examined the mammogram of a patient who had recently undergone breast cancer surgery.

The Loyola University Health System radiologist saw a suspicious pattern of white specks, much like grains of salt. The specks were calcium deposits similar to microcalcifications that sometimes are a sign of early . But it was too early for the patient's breast cancer to have returned because it had been only a month since her lumpectomy.

It turns out the microcalcifications were not from cancer. Rather, they were due to a gel that is sometimes used during to stop bleeding. In a recent article in the American Journal of Roentgenology, Ward and colleagues reported seven cases in which the sealant mimicked malignant microcalcifications in mammograms.

The sealant, FloSeal, "is not recommenderd for use on breast tissue," Ward and colleagues wrote. Ward is Medical Director of Women's Health Imaging and an assistant professor in the Department of Radiology at Loyola University Chicago Stritch School of Medicine.

FloSeal, is among the products surgeons use to stop bleeding when sutures or staples are not sufficient or are impractical. FloSeal generally stops bleeding in two minutes or less. "We hope our study will raise awareness for others who may be using this product or any similar product," said first author Dr. Amy Henkel, a third-year radiology resident at Loyola.

Previous studies have described the use of FloSeal in urological surgery, such as kidney resection, and cardiovascular surgery. FloSeal does not cause imaging problems for those procedures, but should not be used in breast surgery, said study co-author Dr. Richard Cooper, a professor in the Department of Radiology at Stritch.

The study is published in the November, 2008, issue of the American Journal of Roentgenology. In six patients, the microcalcifications caused by FloSeal were seen on six-month follow-up . In the seventh patient, these microcalcifications were seen on a mammogram taken one month after lumpectomy to look for residual malignant calcifications.

Source: Loyola University Health System (news : web)

Explore further: Enzyme that silences DNA activity may be crucially involved in health and cancer

add to favorites email to friend print save as pdf

Related Stories

Mammogram most effective 12 months after radiation treatment

Nov 25, 2008

Breast cancer patients who receive breast-conserving therapy and radiation do not need a follow-up mammogram until 12 months after radiation, despite current American Society of Clinical Oncology (ASCO) and National Comprehensive ...

Breast cancer returns more often in black women

Oct 29, 2007

Contrary to previous studies, African-American women with early-stage breast cancer who have surgery to remove the cancer (lumpectomy) followed by radiation therapy have a higher chance of their cancer coming back in the ...

Recommended for you

Phase 3 study may be game-changer for acute myeloid leukemia

33 minutes ago

Moffitt Cancer Center researchers say clinical trials for a new experimental drug to treat acute myeloid leukemia (AML) are very promising. Patients treated with CPX-351, a combination of the chemotherapeutic drugs cytarabine ...

User comments : 0

More news stories

FDA proposes first regulations for e-cigarettes

The federal government wants to prohibit sales of electronic cigarettes to minors and require approval for new products and health warning labels under regulations being proposed by the Food and Drug Administration.

Vermont moves toward labeling of GMO foods

Vermont lawmakers have passed the country's first state bill to require the labeling of genetically modified foods as such, setting up a war between the behemoth U.S. food industry and an American public that overwhelmingly ...

Brazil enacts Internet 'Bill of Rights'

Brazil's president signed into law on Wednesday a "Bill of Rights" for the digital age that aims to protect online privacy and promote the Internet as a public utility by barring telecommunications companies ...