Brain study could yield clues to schizophrenia

Apr 02, 2009

(PhysOrg.com) -- Scientists have revealed the role of one type of brain cell in the development of a process crucial for memory and learning.

An international study involving the University of Aberdeen has found that these cells - known as basket cells - continue to develop after birth, forming strongly wired networks.

Basket cells control where and when information flows in the brain by acting in what is known as an 'inhibitory" way. Although they make up less than 10% of the nerve cell population in the brain, basket cells efficiently control the activity of the other 90% of our which behave in an excitatory way.

Researchers found that basket cell networks continue to develop their functional capabilities which help generate the fast rhythms in the brain necessary for learning and memory.

Understanding more about the development of basket cells could give more of an insight into as it has been shown that people with this disease show a reduction in the number of these cells and a reduced wiring among them.

Dr Marlene Bartos, a neuroscientist and Reader at the University of Aberdeen's Institute of Medical Sciences, said: "Our work sheds new light on the development of and the emergence of cognitive function.

"Development of basket cell networks seems to be crucial for the emergence of fast brain rhythms which underline mental function.

"What we now need to do is to look in more detail at the function of basket cells in neurodevelopmental diseases such as schizophrenia which seem to be impaired in this illness."

The study has been published in the .

Provided by University of Aberdeen

Explore further: Reducing caloric intake delays nerve cell loss

add to favorites email to friend print save as pdf

Related Stories

Milestone in the regeneration of brain cells

Aug 20, 2007

The majority of cells in the human brain are not nerve cells but star-shaped glia cells, the so called “astroglia”. “Glia means “glue”, explains Götz. “As befits their name, until now these cells have been regarded ...

Rare cell prevents rampant brain activity

Mar 02, 2007

One of the mysteries of the brain is how it avoids ending up in a state of chaos, something which happens only on exceptional occasions, when it can lead to epileptic fits. Scientists at Karolinska Institutet have now uncovered ...

SUMO wrestling in the brain

May 07, 2007

Increasing the amount of SUMO, a small protein in the brain, could be a way of treating diseases such as epilepsy and schizophrenia, reveal scientists at the University of Bristol, UK. Their findings are published online ...

Recommended for you

Reducing caloric intake delays nerve cell loss

12 hours ago

Activating an enzyme known to play a role in the anti-aging benefits of calorie restriction delays the loss of brain cells and preserves cognitive function in mice, according to a study published in the May ...

B vitamins could delay dementia

16 hours ago

(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. ...

If you can remember it, you can remember it wrong

18 hours ago

(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...

Study shows where scene context happens in our brain

20 hours ago

In a remote fishing community in Venezuela, a lone fisherman sits on a cliff overlooking the southern Caribbean Sea. This man –– the lookout –– is responsible for directing his comrades on the water, ...

Clouds in the head

21 hours ago

Many brain researchers cannot see the forest for the trees. When they use electrodes to record the activity patterns of individual neurons, the patterns often appear chaotic and difficult to interpret.

User comments : 0

More news stories

Study says empathy plays a key role in moral judgments

Is it permissible to harm one to save many? Those who tend to say "yes" when faced with this classic dilemma are likely to be deficient in a specific kind of empathy, according to a report published in the scientific journal ...

If you can remember it, you can remember it wrong

(Medical Xpress)—Native peoples in regions where cameras are uncommon sometimes react with caution when their picture is taken. The fear that something must have been stolen from them to create the photo ...

B vitamins could delay dementia

(Medical Xpress)—Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. ...

Reducing caloric intake delays nerve cell loss

Activating an enzyme known to play a role in the anti-aging benefits of calorie restriction delays the loss of brain cells and preserves cognitive function in mice, according to a study published in the May ...

Australia set to cull 10,000 wild horses

A controversial cull of up to 10,000 wild horses in Australia's harsh Outback reportedly began Wednesday in a bid to control the feral animals which officials say are destroying the land.