Therapeutic hypothermia is promising strategy to minimize tissue damage

Mar 19, 2009

Recognition of the benefits of cooling strategies to protect the brain and spinal cord after traumatic injury has led to a wealth of cutting edge research, prime examples of which are featured in a special hypothermia issue of Journal of Neurotrauma, a peer-reviewed journal published by Mary Ann Liebert, Inc.

The issue includes a series of original articles presenting experimental and clinical evidence to support the use of modest in specific conditions. These reports emanated from presentations at the 2nd International Brain Hypothermia Symposium and were selected for publication in the Journal by Guest Editors W. Dalton Dietrich, PhD, and M. Ross Bullock, MD, PhD, both from the University of Miami Miller School of Medicine and Patrick M. Kochanek, MD, from the University of Pittsburgh.

In his Introduction, Dr. Dietrich points out that many factors determine whether hypothermic therapy will be beneficial, including "how early hypothermic therapy is initiated after the insult, the duration of the hypothermic period, the degree of hypothermia, as well as the rewarming protocol. Thus, it is important that basic research studies are continuing in clinical relevant animal models to address these important questions."

The issue explores several aspects of hypothermia, including studies in animal models, its use in the operating room, and its role in the treatment of , stroke and subarachnoid hemorrhage, traumatic brain (TBI) and spinal cord injury, and pediatric TBI and asphyxia.

Mackensen et al. focus on "Perioperative Hypothermia: Use and Therapeutic Implications," and Kim et al. describe "The Use of Pre-Hospital After Resuscitation from Out-of-Hospital Cardiac Arrest." Kochanek et al. collaborate on two articles on in pediatric populations, one describing the Safar Vision, and the other focusing on applications in pediatric cardiac arrest. Shankaran presents "Neonatal Encephalopathy: Treatment with Hypothermia," and Bullock et al. provides an overview of "Current and Future Role of Therapeutic Hypothermia."

More information: The issue will be available free online at www.liebertpub.com/neu

Source: Mary Ann Liebert

Explore further: Improving babies' language skills before they're even old enough to speak

add to favorites email to friend print save as pdf

Related Stories

Norwegian scientists study hypothermia

Jul 18, 2006

Norwegian scientists may have ruled out insufficient oxygen supply to the heart as a critical variable in whether a mammal's heart survives hypothermia.

Post-cardiac arrest care key to survival

Oct 23, 2008

The urgent need for treatment doesn't end when a person regains a pulse after suffering sudden cardiac arrest — healthcare providers need to move quickly into post-cardiac arrest care to keep a person alive and ensure the ...

New stem cell therapy may aid the repair of damaged brains

May 31, 2008

According to some experts, newly born neuronal stem cells in the adult brain may provide a therapy for brain injury. But if these stem cells are to be utilized in this way, the process by which they are created, neurogenesis, ...

Recommended for you

What happens in our brain when we unlock a door?

4 hours ago

People who are unable to button up their jacket or who find it difficult to insert a key in lock suffer from a condition known as apraxia. This means that their motor skills have been impaired – as a result ...

Sport can help multiple sclerosis patients

8 hours ago

A study developed at the Miguel Hernández University of Elche (Spain) has preliminarily concluded that people with multiple sclerosis may reduce perceived fatigue and increase mobility through a series of ...

Obama's BRAIN initiative gets more than $300 million

12 hours ago

President Barack Obama's initiative to study the brain and improve treatment of conditions like Alzheimer's and autism was given a boost Tuesday with the announcement of more than $300 million in funds.

User comments : 1

Adjust slider to filter visible comments by rank

Display comments: newest first

E_L_Earnhardt
not rated yet Mar 19, 2009
Hypothermia also has the option of curing cancer!
Try it and see!