New tool to fast-track genetic gain in sheep

Jan 14, 2009
New tool to fast-track genetic gain in sheep
Experimental sheep at CSIRO's FD McMaster Laboratory, Armidale NSW. Photo by: CSIRO

(PhysOrg.com) -- Scientists from CSIRO are part of an international team that today launched a new genomic tool which is set to transform the future selection and breeding of sheep around the world.

Called the Ovine SNP50 BeadChip, this cutting-edge tool will enable researchers to characterise the genetic variation at more than 50,000 Single Nucleotide Polymorphisms (SNP) in the sheep genome. This will help pinpoint the small genetic differences that produce a variety of commercially important traits in sheep such as improved growth rate, fertility, parasite resistance, and healthier meat products.

The research has been undertaken by the International Sheep Genomics Consortium (ISGC). This partnership of scientists and funding agencies is developing a range of publicly available genomic resources to help scientists find the genes and develop DNA markers associated with traits critical to the sheep meat and wool industries in their countries.

Working in partnership with Illumina, Inc., a global company headquartered in San Diego California, the Ovine SNP50 BeadChip has today been made available to research groups.

According to ISGC Secretary and CSIRO Livestock Industries molecular geneticist Dr James Kijas, there has been extremely strong demand from scientists for the SNP chip.

“In Australia, the priority is to use the new tool to speed up the development of genetic markers which will fast-track genetic gain, providing major benefits for producers,” he said.

“In addition, scientists will use the chip to help unravel the process of sheep domestication and impact of selection. A major aim of the ISGC is to use the chip to collect data from over 60 breeds of sheep and their wild relatives. This will tell us a lot about the history of the species and reveal which parts of the genome have been under selection for economically important traits,” Dr Kijas said.

The initial sheep genome sequencing was performed in parallel at the Otago University, Dunedin, New Zealand and the Human Genome Sequencing Centre at the Baylor College of Medicine, Houston, Texas, with additional sequencing subsequently undertaken by Illumina. The genome assembly, SNP detection and selection of SNP was undertaken jointly by groups at AgResearch and CSIRO and used by Illumina to create the Ovine SNP50 BeadChip.

Provided by CSIRO

Explore further: Researchers record sight neurons in jumping spider brain

add to favorites email to friend print save as pdf

Related Stories

Being sheepish about climate adaptation

Sep 23, 2014

For thousands of years, man has domesticated animals, selecting the best traits possible for survival. Now, livestock such as sheep offer an intriguing animal to examine adaptation to climate change, with a genetic legacy ...

Recommended for you

Secret wing colours attract female fruit flies

1 hour ago

Bright colours appear on a fruit fly's transparent wings against a dark background as a result of light refraction. Researchers from Lund University in Sweden have now demonstrated that females choose a mate ...

Crowdsourced power to solve microbe mysteries

2 hours ago

University of New South Wales scientists hope to unlock the secrets of millions of marine microbes from waters as far apart as Sydney's Botany Bay and the Amazon River in Brazil, with the help of an international ...

Pigeons and people play the odds when rewards are higher

3 hours ago

(Phys.org) —If you were weighing the risks, would you choose to receive a guaranteed $100, or take a 50/50 chance of winning either $200 or nothing? Researchers at the University of Alberta have shown that ...

User comments : 0