Women are more likely than men to die in hospital from severe heart attack

Dec 08, 2008

Men and women have about the same in-hospital death rate for heart attack — but women are twice as likely to die if hospitalized for a more severe type of heart attack, according to a report in Circulation: Journal of the American Heart Association.

Among patients with ST elevation myocardial infarction (STEMI) in a recent study, the death rate was 10.2 for women compared to 5.5 for men. Researchers said the women were older and had higher overall baseline risk profiles than men. However, the study also found that some recommended treatments are delayed and underused in women.

Researchers analyzed data from the American Heart Association's Get With The Guidelines (GWTG) program to determine if recent efforts to improve heart attack care at hospitals had closed the gender disparity gap. They reviewed the clinical characteristics, treatments and outcomes of more than 78,000 patients diagnosed with myocardial infarction admitted to 420 hospitals between 2001 and 2006.

"The finding that bears the most emphasis is that among both men and women presenting to Get With The Guidelines participating hospitals, there were no clinically meaningful differences in in-hospital survival after heart attack, once we factored in differences, such as age and other existing illnesses," said Hani Jneid, M.D., lead author of the study and assistant professor of Cardiovascular Medicine at Baylor College of Medicine in Houston, Texas.

A decade ago, women had an overall higher death rate after heart attack compared with men. This suggests that these hospitals are now using high rates of evidence-based therapies shown to increase survival after heart attack.

"However, the finding of persistently higher death rates among women experiencing the more severe type of heart attack (STEMI) and the persistent gender gap in certain aspects of care underscore the existing opportunities to enhance post-heart attack care among women," Jneid said.

In the study, Jneid and colleagues found that, compared to men, women were:

-- 14 percent less likely to receive early aspirin;
-- 10 percent less likely to receive beta blockers;
-- 25 percent less likely to receive reperfusion therapy (to restore blood flow);
-- 22 percent less likely to receive reperfusion therapy within 30 minutes of hospital arrival; and
-- 13 percent less likely to receive angioplasty within 90 minutes of hospital arrival.

"We could not determine in this study to which extent these differences were due to physicians' failures to administer optimal therapies to women vs. appropriate decision-making based on biological and other differences between men and women," Jneid said.

Furthermore, researchers found that women admitted with a STEMI were about twice as likely to die in the first 24 hours of hospitalization as men.

"Although STEMI is not as common among women as it is among men, it is a concern that there is still this gap in mortality between men and women after the more severe heart attack," said Laura Wexler, M.D., co-author of the study and senior associate dean at the University of Cincinnati College of Medicine.

Get With The Guidelines helps improve physicians' awareness of proven post-heart attack therapies, said Gregg C. Fonarow, M.D., chairman of the Get With The Guidelines steering committee.

"As part of this effort, the American Heart Association has been collecting data from a large number of hospitals about the treatments and outcomes of therapy for heart attack victims," said Fonarow, a professor of cardiovascular medicine at UCLA. Thus, GWTG "has not only helped improve care but also created a powerful research tool," Fonarow said.

Source: American Heart Association

Explore further: Ebola mistakes should serve a lesson says WHO

add to favorites email to friend print save as pdf

Related Stories

Davos elites warned about catastrophic cyberattacks

4 hours ago

Attacks on power plants, telecommunications and financial systems, even turning all of Los Angeles' traffic lights green: Davos elites were warned Saturday of the terrifying possibilities of modern cyber ...

Recommended for you

Ebola mistakes should serve a lesson says WHO

21 minutes ago

The World Health Organization's chief admitted on Sunday that the UN agency had been caught napping on Ebola, saying it should serve as a lesson to avoid similar mistakes in future.

British Ebola nurse discharged from hospital

7 hours ago

A British nurse who contracted Ebola while working as a volunteer in Sierra Leone said she was "happy to be alive" as she was discharged from hospital on Saturday having made a full recovery.

Tide turning in Ebola fight after hard lessons

Jan 24, 2015

A top U.N. official in the fight against Ebola greeted just three patients at one treatment center he visited this week in Sierra Leone. Families in Liberia are no longer required to cremate the remains of ...

Just five Ebola cases left in Liberia: UN

Jan 24, 2015

The United Nations said on Saturday Liberia was dealing with just five remaining cases of Ebola, in the clearest sign yet that the country is nearing the end of the outbreak.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.