Have numbness, pain or muscle weakness? Guidelines identify best tests for neuropathy

Dec 03, 2008

New guidelines developed by the American Academy of Neurology find a combination of blood tests and other specialized assessments appear to be the most helpful tests for finding the cause of neuropathy. Also known as neuritis or distal symmetric polyneuropathy, this common nerve problem affects people of all ages. The guidelines are published in the December 3, 2008, online issue of Neurology, the medical journal of the American Academy of Neurology.

Neuropathy affects one in 50 people in the general population and one in 12 over the age of 55. It usually causes numbness, tingling or pain, often starting in the feet and moving to the hands. Symptoms spread slowly and evenly up the legs and arms. Muscle wasting and weakness can also occur. Neuropathy takes many forms and has many causes. The most common cause is diabetes. Other common causes are heredity, alcohol abuse, poor nutrition and autoimmune processes. Not all of the causes are known.

"There are many people with a neuropathy who have been walking around for years without having been diagnosed and treated," said guidelines author John D. England, MD, Chairman of the Department of Neurology at Louisiana State University Health Sciences Center in New Orleans and Fellow of the American Academy of Neurology. "Both neurologists and people with neuropathy need to know that the appropriate choice of tests is critical to accurate diagnosis."

To develop the guidelines, the authors analyzed all available scientific studies on the topic.

The guidelines recommend that doctors obtain certain blood tests for all patients with numb, painful feet. "People with suspected nerve problems should talk to their doctors about screening tests, especially blood glucose, vitamin B12 level and serum protein levels, since these tests can often point to common causes of neuropathy," said England. The guidelines recommend tailored genetic testing for accurately diagnosing certain neuropathies that run in families.

The guidelines further recommend that doctors consider a combination of specialized tests to accurately evaluate neuropathies with autonomic dysfunction. These tests, known as autonomic tests, measure the action of the tiny nerves that control such functions as sweating, heart rate and blood pressure. Skin biopsy may also be useful to diagnose loss of tiny nerve fibers in the skin.

Source: American Academy of Neurology

Explore further: Filipino tests negative for Middle East virus

add to favorites email to friend print save as pdf

Related Stories

Environmental hormones – tiny amounts, big effects

Apr 02, 2014

Empty nets and few species – environmental hormones are believed responsible for the diminishing numbers of fish. How damaging are these substances really, though? Studies that depict a complete picture ...

Heavily-contaminated water found in Thames Valley

Feb 18, 2014

High-levels of faecal-contaminated, disease-ridden bacteria have been found in floodwater in the Thames Valley Wraysbury, Berkshire in University of Reading analysis for Sky News and Channel 4 News.

Cleaning up space debris with sailing satellites

Feb 03, 2014

Since the birth of space flight in 1957, the number of man-made objects orbiting the Earth has grown every year. There are now more than 15,000 such objects larger than 10cm, at least those that we know of. ...

Recommended for you

Two expats die of MERS in Saudi commercial hub

1 hour ago

Two foreigners died of MERS in the Saudi city of Jeddah, the health ministry said Saturday, as fears rise over the spreading respiratory virus in the kingdom's commercial hub.

UAE reports 12 new cases of MERS

1 hour ago

Health authorities in the United Arab Emirates have announced 12 new cases of infection by the MERS coronavirus, but insisted the patients would be cured within two weeks.

Filipino tests negative for Middle East virus

13 hours ago

A Filipino nurse who tested positive for the Middle East virus has been found free of infection in a subsequent examination after he returned home, Philippine health officials said Saturday.

US orders farms to report pig virus infections

Apr 18, 2014

The U.S. government is starting a new program to help monitor and possibly control the spread of a virus that has killed millions of pigs since showing up in the country last year.

User comments : 0

More news stories

UAE reports 12 new cases of MERS

Health authorities in the United Arab Emirates have announced 12 new cases of infection by the MERS coronavirus, but insisted the patients would be cured within two weeks.

Filipino tests negative for Middle East virus

A Filipino nurse who tested positive for the Middle East virus has been found free of infection in a subsequent examination after he returned home, Philippine health officials said Saturday.

NASA's space station Robonaut finally getting legs

Robonaut, the first out-of-this-world humanoid, is finally getting its space legs. For three years, Robonaut has had to manage from the waist up. This new pair of legs means the experimental robot—now stuck ...