A rare case of collagenous colitis presenting as protein-losing enteropathy

Nov 03, 2008

Since the first report in 1976, collagenous colitis has been associated with a variety of conditions, including use of non-steroidal anti-inflammatory drugs and proton pump inhibitors. This condition is characterized by chronic watery diarrhea and abnormal deposition of collagen beneath the colonic epithelium. Severe hypoproteinemia due to enteric protein loss is rare unless accompanied by small bowel malabsorption syndrome. To the best of authors' knowledge, only 1 case of collagenous colitis associated with protein-losing enteropathy (PLE) in the absence of small bowel disease has been reported.

An article to be published on October 21, 2008 in the World Journal of Gastroenterology addresses this case. The research team led by Keiko Yamagami from Osaka City General Hospital of Japan reported herein another case of collagenous colitis associated with PLE without small bowel disease, in which PLE was diagnosed by 99mTc-human albumin scintigraphy.

They have reported the case of a patient with collagenous colitis who presented with PLE. Prednisolone treatment ameliorated diarrhea and hypoproteinemia.

Collagenous colitis should be included in the differential diagnosis of chronic diarrhea with hypoproteinemia to achieve appropriate management. Treatment with prednisolone may be effective for PLE associated with collagenous colitis.

Source: World Journal of Gastroenterology

Explore further: Nigeria confirms Liberian man died of Ebola in Lagos (Update)

add to favorites email to friend print save as pdf

Related Stories

Physicists discuss quantum pigeonhole principle

1 hour ago

The pigeonhole principle: "If you put three pigeons in two pigeonholes at least two of the pigeons end up in the same hole." So where's the argument? Physicists say there is an important argument. While the ...

Giant crater in Russia's far north sparks mystery

4 hours ago

A vast crater discovered in a remote region of Siberia known to locals as "the end of the world" is causing a sensation in Russia, with a group of scientists being sent to investigate.

NASA Mars spacecraft prepare for close comet flyby

4 hours ago

NASA is taking steps to protect its Mars orbiters, while preserving opportunities to gather valuable scientific data, as Comet C/2013 A1 Siding Spring heads toward a close flyby of Mars on Oct. 19.

Giant anteaters kill two hunters in Brazil

4 hours ago

Giant anteaters in Brazil have killed two hunters in separate incidents, raising concerns about the animals' loss of habitat and the growing risk of dangerous encounters with people, researchers said.

Recommended for you

User comments : 0