An epidemiologic study of microscopic colitis in Turkey

Oct 07, 2008

The research team led by Levent Erdem from Şişli Etfal Teaching and Research Hospital of Turkey investigated the prevalence and demography of microscopic colitis in patients with diarrhea of unknown etiology and normal colonoscopy in Turkey. This will be published on 21 July 2008, in the World Journal of Gastroenterology addresses this question.

Between March 1998 to July 2005, 129 patients with chronic non-bloody diarrhea of unexplained etiology who had undergone full colonoscopy with no obvious abnormality were included in the study. Two biopsies were obtained from all colonic segments and terminal ileum for diagnosis of microscopic colitis. Lymphocytic colitis was diagnosed in 12 (9%) patientsand collagenous colitis. Biopsy of Turkish patients with the diagnosis of chronic non-bloody diarrhea of unexplained etiology and normal colonoscopic findings will reveal microscopic colitis in approximately 10%. Authors found lymphocytic colitis as 4 times more frequent than collagenous colitis in those patients.

Considering 11.5% of the patients with chronic diarrhea of unknown etiology and normal colonoscopy would have microscopic colitis, biopsy should be taken during colonoscopy in this subset of patients. Although the number of the cases was not enough to answer the question of how many biopsies should be taken and from which part of the colon, the fact that histopathological criteria were determined on all colonic regions in patients with lymphocytic colitis on whom biopsy was performed is promising in terms of diagnostic convenience.

This is an epidemiologic study confirming findings reported from other countries about the frequency of lymphocytic and collagenous colitis and the importance of biopsies for the diagnosis.

Source: World Journal of Gastroenterology

Explore further: The early cost of HIV: Inflammatory response breaks down intestinal lining, but help may come from friendly bacteria

add to favorites email to friend print save as pdf

Related Stories

FIXD tells car drivers via smartphone what is wrong

10 hours ago

A key source of anxiety while driving solo, when even a bothersome back-seat driver's comments would have made you listen: the "check engine" light is on but you do not feel, smell or see anything wrong. ...

Team pioneers strategy for creating new materials

11 hours ago

Making something new is never easy. Scientists constantly theorize about new materials, but when the material is manufactured it doesn't always work as expected. To create a new strategy for designing materials, ...

Shell files new plan to drill in Arctic

12 hours ago

Royal Dutch Shell has submitted a new plan for drilling in the Arctic offshore Alaska, more than one year after halting its program following several embarrassing mishaps.

Aging Africa

12 hours ago

In the September issue of GSA Today, Paul Bierman of the University of Vermont–Burlington and colleagues present a cosmogenic view of erosion, relief generation, and the age of faulting in southernmost Africa ...

Recommended for you

Ebola in mind, US colleges screen some students

Aug 29, 2014

University students from West Africa may be subject to extra health checks when they arrive to study in the United States as administrators try to insulate their campuses from the worst Ebola outbreak in ...

User comments : 0