6 environmental research studies reveal critical health risks from plastic

Oct 02, 2008

Exposure to Bisphenol A (BPA), phthalates and flame retardants (PBDEs) are strongly associated with adverse health effects on humans and laboratory animals. A special section in the October 2008 issue of Environmental Research, "A Plastic World" provides critical new research on environmental contaminants and adverse reproductive and behavioral effects.

Plastic products contain "endocrine disrupting chemicals" that can block the production of the male sex hormone testosterone (phthalates used in PVC plastic), mimic the action of the sex hormone estrogen (bisphenol A or BPA used in polycarbonate plastic), and interfere with thyroid hormone (brominated flame retardants or PBDEs used in many types of plastic).

Two articles report very similar changes in male reproductive organs in rats and humans related to fetal exposure to phthalates. Two articles show that fetal exposure to BPA or PBDEs disrupts normal development of the brain and behavior in rats and mice. Two other articles provide data that these chemicals are massively contaminating the oceans and causing harm to aquatic wildlife.

The other studies integrate new laboratory research with a broader view reflecting exposures to a variety of chemicals in plastic. These ubiquitous chemicals found in many plastics act independently and together to adversely affect human, animal and environmental health.

The articles show amongst others the massive contamination of the Pacific Ocean with plastic, and the amount of contamination has increased dramatically in recent years; animal brain structure, brain chemistry and behavioral effects from exposure to BPA and "phthalate syndrome" in rats' male offspring.

"For the first time a series of articles will appear together that identify that billions of kilograms of a number of chemicals used in the manufacture of different types of plastic can leach out of plastic products and cause harm to the brain and reproductive system when exposure occurs during fetal life or prior to weaning," emphasized Dr. Frederick vom Saal, Guest Editor of the "Plastic World".

"Not only are these studies of scientific importance, they also contribute to the ongoing US congressional hearings involving the Food and Drug Administration," remarked Gert-Jan Geraeds, Publisher of Environmental Research, "As such, "The Plastic World" has a broader societal impact and raises awareness of increasingly important environmental issues".

References:

Frederick S. vom Saal, Stefano Parmigiani, Paola L. Palanza, Lorne G. Everett, Richard Ragaini, The plastic world: Sources, amounts, ecological impacts and effects on development, reproduction, brain and behavior in aquatic and terrestrial animals and humans, Environmental Research, 108 (2008), pp. 127 - 130

Charles James Moore, Synthetic polymers in the marine environment: A rapidly increasing, long-term threat, Environmental Research, 108 (2008), pp. 131 – 139

Jörg Oehlmann, Matthias Oetken, Ulrike Schulte-Oehlmann, A critical evaluation of the environmental risk assessment for plasticizers in the freshwater environment in Europe, with special emphasis on bisphenol A and endocrine disruption, Environmental Research, 108 (2008), pp. 140 – 149

Paola Palanza, Laura Gioiosa, Frederick S. vom Saal, Stefano Parmigiani, Effects of developmental exposure to bisphenol A on brain and behavior in mice, Environmental Research, 108 (2008), pp. 150 – 157

Chris E. Talsness, Overview of toxicological aspects of polybrominated diphenyl ethers: A flame-retardant additive in several consumer products, Environmental Research, 108 (2008), pp. 158 – 167

Kembra L. Howdeshell, Cynthia V. Rider, Vickie S. Wilson, L. Earl Gray Jr., Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats, Environmental Research, 108 (2008), pp. 168 – 176

Shanna H. Swan, Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans, Environmental Research, 108 (2008), pp.

Source: Elsevier

Explore further: Off-season doesn't allow brain to recover from football hits, study says

add to favorites email to friend print save as pdf

Related Stories

Environmentally compatible organic solar cells

7 hours ago

Environmentally compatible production methods for organic solar cells from novel materials are in the focus of "MatHero". The new project coordinated by Karlsruhe Institute of Technology (KIT) aims at making ...

Beating heart powers pacemaker

Apr 10, 2014

(Phys.org) —An interdisciplinary research team including Northwestern University's Yonggang Huang has developed a flexible medical implant that harvests the energy of the beating heart. Such a device could ...

Filter helps recover 80% of gold in mobile phone scrap

Apr 10, 2014

Mobile phone scrap can contain precious metals, such as gold and copper. VTT Technical Research Centre of Finland has developed a biological filter made of mushroom mycelium mats enabling recovery of as much ...

Researching materials to optimize battery performance

Apr 08, 2014

Creating environment friendly energy storage systems, non-explosive and with charge/discharge long-term cycles, motivated a group of scientists from the Autonomous Metropolitan University, Campus Iztapalapa ...

Efficient operation of wastewater treatment plants

Apr 08, 2014

The German Federal Environmental Foundation (Deutsche Bundesstiftung Umwelt) announces the launch of a groundbreaking project for which the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) is developing sophisticated ...

Recommended for you

US judge overturns state's abortion law (Update)

4 hours ago

A federal judge on Wednesday overturned a North Dakota law banning abortions when a fetal heartbeat can be detected, as early as six weeks into pregnancy and before many women know they're pregnant.

Changing cows' diet could help tackle heart disease

8 hours ago

Adding oilseed to a cow's diet can significantly reduce the harmful saturated fat found in its milk without compromising the white stuff's nutritional benefits, according to research by the University of ...

User comments : 2

Adjust slider to filter visible comments by rank

Display comments: newest first

bwanajohn
not rated yet Oct 03, 2008
This is "science by press release". Every time I see headlines like this and read the "study" there are serious breaches in the science to come to the conclusions presented. We have drifted from "dosage makes the poison" to anectodal evidence of a "possible link". Until I see solid dosage based evidence, I will remain skeptical.
grainger
not rated yet Oct 03, 2008
Another report issued by the European Food Safety Administration stated that there was a critical difference in the way rats and humans dealt with BPA. Rats metabolized it; whereas, humans passed it quickly through their systems. Something is highly suspect about these latest alarming reports.

More news stories

Researchers see hospitalization records as additional tool

Comparing hospitalization records with data reported to local boards of health presents a more accurate way to monitor how well communities track disease outbreaks, according to a paper published April 16 in the journal PLOS ON ...

Ebola virus in Africa outbreak is a new strain

Scientists say that the Ebola (ee-BOH'-lah) virus that has killed scores of people this year in Guinea (GIH'-nee) is a new strain. That means it did not spread there from outbreaks in some other African nations.