UCLA imaging study suggests Alzheimer's drug may help mild memory loss

Jul 30, 2008

Alzheimer's disease is the end result of gradual, progressive brain aging. Positron emission technology (PET) scans of patients' brains typically reveal a decreased rate of metabolism, a hallmark of the disorder.

A small sample of adults with mild age-related memory loss was randomly assigned a daily placebo or Aricept, a drug that treats Alzheimer's symptoms. Both groups underwent PET brain scans before and after 18 months of treatment. The brains of people given Aricept showed an increased rate of metabolism and looked more normal than the brains of those who took the placebo. Both groups scored the same on memory tests, however, implying that PET scans may be more sensitive than neuropsychological tests in detecting drugs' effects.

The research suggests that the treatment of early symptoms of memory loss may protect the brain and help people with mild age-related memory impairment. The finding also shows how PET offers researchers a tool for tracking the effectiveness of drugs prescribed to treat age-related cognitive decline.

The findings will be presented July 30 at the "Hot Topics" poster session of the International Conference on Alzheimer's Disease 2008, hosted by the Alzheimer's Association.

Source: University of California - Los Angeles

Explore further: Sierra Leone faces criticism over Ebola shutdown

add to favorites email to friend print save as pdf

Related Stories

In Alzheimer's diagnosis, many heads better than one

Jan 26, 2011

In a marriage of two disciplines that don’t often overlap — politics and medicine — a study by Matthew Gabel, PhD, professor of political science in Arts & Sciences at Washington University ...

FDA panel sees promise in Alzheimer's imaging drug

Jan 20, 2011

(AP) -- A federal panel of medical experts said Thursday a first-of-a-kind imaging chemical designed to help screen for Alzheimer's disease could be useful pending additional study and training for physicians.

Recommended for you

Sierra Leone faces criticism over Ebola shutdown

6 hours ago

Sierra Leone began the second day of a 72-hour nationwide shutdown aimed at containing the spread of the deadly Ebola virus on Saturday amid criticism that the action was a poorly planned publicity stunt.

Presence of peers ups health workers' hand hygiene

20 hours ago

(HealthDay)—The presence of other health care workers improves hand hygiene adherence, according to a study published in the October issue of Infection Control and Hospital Epidemiology.

Sierra Leone streets deserted as shutdown begins

Sep 19, 2014

Sierra Leone's normally chaotic capital resembled a ghost town on Friday as residents were confined to their homes for the start of a three-day lockdown aimed at halting the deadly Ebola epidemic.

Sierra Leone launches controversial Ebola shutdown

Sep 19, 2014

Sierra Leone on Friday launched a controversial three-day shutdown to contain the deadly spread of the Ebola virus, as the UN Security Council declared the deadly outbreak a threat to world peace.

User comments : 0