Managing noncommunicable diseases in Africa: what can we learn from TB control?

Jun 10, 2008

Non-communicable diseases (NCDs), such as heart disease, diabetes, stroke, asthma, epilepsy, and mental illness, are becoming a major burden in sub-Saharan Africa but are often poorly managed in routine health care settings, say Anthony Harries from the Malawi Ministry of Health and colleagues in this week's PLoS Medicine. The authors argue that better management could be achieved by learning from the success of tuberculosis (TB) control programs.

Sub-Saharan Africa faces frequent stock interruptions of essential drugs for managing non-communicable diseases, say the authors. Untreated hypertension is blamed for high rates of illness and death from stroke in urban and rural Tanzania and rural South Africa, and across the continent only a small proportion of patients with epilepsy receive drug treatment at any one time, mainly due to poor health care delivery systems and unavailability of drugs.

There is a growing burden of diabetes and its complications, and many patients with type 1 diabetes mellitus have extremely short life expectancies in sub-Saharan Africa. Even in specialist centers, patients with asthma may still receive sub-standard care and have poor access to essential medications.

Dr Harries and colleagues propose a solution to the problem of managing these diseases—health professionals and policy makers should learn from TB control programs. In particular, they should learn from a five-point TB control framework called "DOTS" ("directly observed therapy, short course"). The five-point policy package of DOTs involves political commitment; finding cases of TB by testing the sputum of patients presenting to health care facilities; a standardized, short-course of medications for treating TB with one of the drugs (rifampicin) given under direct observation by a health care worker, community, or family member; a monitoring and evaluation system; and an interrupted drug supply.

These five points, say the authors, provide lessons for NCD control. Human and financial resources—and therefore political commitment—are needed to develop, implement, and supervise standardized approaches to managing NCDs. The only feasible and affordable way of identifying patients with NCDs is to diagnose and treat those who present to health facilities. These facilities should adopt standardized ways of treating NCDs, as well as monitoring and evaluating them, and systems should be in place to ensure regular drug supply.

"Within a country," say the authors, "the DOTS paradigm for NCDs should be piloted in one or two facilities, and lessons learnt in these facilities should be used to assist national roll-out within the public sector."

Citation: Harries AD, Jahn A, Zachariah R, Enarson D (2008) Adapting the DOTS framework for tuberculosis control to the management of non-communicable diseases in sub-Saharan Africa. PLoS Med 5(6): e124. -- www.plos.org/press/plme-05-06-harries.pdf

Source: Public Library of Science

Explore further: Swine flu pandemic of 2009 more deadly for younger adults, study finds

add to favorites email to friend print save as pdf

Related Stories

Improving communication during disasters

May 13, 2013

A small armband which can be attached to the injured. An information board containing a complete visual record of events. This is technology helping to improve communications during major national disasters.

Pollen: You can run, but you can't hide

May 08, 2013

(Phys.org) —It's the yellowish coating on cars. It floats on ponds, blows with the spring breeze and serves as a potent irritant to allergy sufferers. Now a NASA team is targeting pollen—and its work ...

Gold nanoparticles: A new delivery for cancer drugs

May 08, 2013

(Phys.org) —The protein tumor necrosis factor-alpha (TNF-alpha) is a powerful weapon in the arsenal to control cancer. Unfortunately, as is the case with many potent cancer therapies, the use of TNF-alpha as an anti-cancer ...

Recommended for you

WHO: Scientific red tape mars efforts vs. virus

5 hours ago

International efforts to combat a new pneumonia-like virus that has now killed 22 people are being slowed by unclear rules and competition for the potentially profitable rights to disease samples, the head ...

Ferrets, pigs susceptible to H7N9 avian influenza virus

7 hours ago

Chinese and U.S. scientists have used virus isolated from a person who died from H7N9 avian influenza infection to determine whether the virus could infect and be transmitted between ferrets. Ferrets are often used as a mammalian ...

User comments : 0

More news stories

Controlling mood through the motions of mitochondria

(Medical Xpress)—Regulating the distribution of power in neurons is done by a system that makes the national electric grid look simple by comparison. Each neuron has several thousand mitochondria confined ...

Ferrets, pigs susceptible to H7N9 avian influenza virus

Chinese and U.S. scientists have used virus isolated from a person who died from H7N9 avian influenza infection to determine whether the virus could infect and be transmitted between ferrets. Ferrets are often used as a mammalian ...

A quantum simulator for magnetic materials

Physicists understand perfectly well why a fridge magnet sticks to certain metallic surfaces. But there are more exotic forms of magnetism whose properties remain unclear, despite decades of intense research. ...

A hidden population of exotic neutron stars

(Phys.org) —Magnetars – the dense remains of dead stars that erupt sporadically with bursts of high-energy radiation - are some of the most extreme objects known in the Universe. A major campaign using ...