Lab will pay to infect people with malaria

Mar 06, 2008

Scientists in Seattle plan to pay people to catch malaria in order to test the safety and efficacy of new vaccines.

The Seattle Biomedical Research Institute and the PATH Malaria Vaccine Initiative are collaborating to build a Human Challenge Center at SBRI to test new interventions against the deadly malaria parasite. "This center will allow us to greatly increase our ability to evaluate whether a new vaccine formulation should advance to testing in clinical trials in malaria-endemic populations," Dr. Christian Loucq of MVI said Wednesday in a statement.

The laboratory's Malaria Clinical Trials Center will be one of only a handful of facilities of its kind in the world. Volunteers inoculated with a malaria vaccine candidate will be deliberately infected with malaria through the bite of malaria-infected mosquitoes to assess whether or not the candidate vaccine can prevent or delay malaria infection.

The Seattle Times said the strain of malaria used in the testing is a cloned strain that can be quickly cured. More than 900 people have participated in similar tests at Walter Reed Army Institute of Research. There are also labs in Britain and the Netherlands, the newspaper said.

Copyright 2008 by United Press International

Explore further: Experts denounce clinical trials of unscientific, 'alternative' medicines

add to favorites email to friend print save as pdf

Related Stories

Bill Gates says innovation can leverage change

Jan 25, 2010

(AP) -- The needs of the poor are greater than the money available to help them, but that's not enough to discourage Bill Gates in his work as co-chair of the world's largest charitable foundation.

Mosquitoes deliver malaria 'vaccine' through bites

Jul 29, 2009

In a daring experiment in Europe, scientists used mosquitoes as flying needles to deliver a "vaccine" of live malaria parasites through their bites. The results were astounding: Everyone in the vaccine group acquired immunity ...

Forgotten evolutionist lives in Darwin's shadow

Jun 28, 2009

(AP) -- As he trudges past chest-high ferns and butterflies the size of saucers, George Beccaloni scours a jungle hilltop overlooking the South China Sea for signs of a long-forgotten Victorian-era scientist.

Herpes medication does not reduce risk of HIV transmission

May 08, 2009

A recently completed international multi-center clinical trial has found that acyclovir, a drug widely used as a safe and effective treatment to suppress herpes simplex virus-2 (HSV-2), which is the most common cause of genital ...

Recommended for you

Obese British man in court fight for surgery

Jul 11, 2011

A British man weighing 22 stone (139 kilograms, 306 pounds) launched a court appeal Monday against a decision to refuse him state-funded obesity surgery because he is not fat enough.

2008 crisis spurred rise in suicides in Europe

Jul 08, 2011

The financial crisis that began to hit Europe in mid-2008 reversed a steady, years-long fall in suicides among people of working age, according to a letter published on Friday by The Lancet.

New food labels dished up to keep Europe healthy

Jul 06, 2011

A groundbreaking deal on compulsory new food labels Wednesday is set to give Europeans clear information on the nutritional and energy content of products, as well as country of origin.

Overweight men have poorer sperm count

Jul 04, 2011

Overweight or obese men, like their female counterparts, have a lower chance of becoming a parent, according to a comparison of sperm quality presented at a European fertility meeting Monday.

User comments : 0