Low-fat diet possibly linked to lower risk of ovarian cancer

Oct 09, 2007

A low-fat diet may decrease the risk of ovarian cancer in postmenopausal women, according to a study published online October 9 in the Journal of the National Cancer Institute.

Previous reports from the Women’s Health Initiative Dietary Modification Randomized Controlled Trial examined the effect of a low-fat diet on the risk of breast and colorectal cancer in postmenopausal women, but it was not yet known whether the same diet would alter ovarian cancer risk.

Ross Prentice, Ph.D., of Fred Hutchison Cancer Research Center in Seattle and colleagues analyzed data from the dietary modification trial to see if the changes in the women’s diets decreased the risk of ovarian and endometrial cancer and invasive cancers overall. In the trial, nearly 20,000 women were randomly assigned to the diet modification group and almost 30,000 women ate their normal diet.

The women participating in the diet were asked to reduce their fat intake to 20 percent of their overall diet, as well as eat at least five serving of fruits and vegetables a day and at least six servings of whole grains. They were followed for an average of eight years.

The risk of ovarian cancer was similar in the two groups for the first four years of follow-up, but it was reduced in the dieting group during the following four years. Women who had the highest fat intake before the trial saw the greatest reduction in risk. There was no difference in endometrial cancer risk between the two groups, but a trend toward a reduction in invasive cancers overall was suggested in the dieting group. It was not, however, statistically significant.

“Ongoing …follow-up of trial participants may provide additional valuable assessment of the effects of a low-fat dietary pattern on these and other cancer incidence rates,” the authors write.

Source: Journal of the National Cancer Institute

Explore further: Prosocial internet support group not beneficial for breast cancer

add to favorites email to friend print save as pdf

Related Stories

Coming up for air

Oct 29, 2014

Sometimes you've got to hit bottom to battle your way back up. In 1992, the United Nations cited Mexico City as having the worst air quality in the world, with so much pollution that birds sometimes dropped ...

Recommended for you

Immune checkpoint inhibitors may work in brain cancers

Nov 21, 2014

New evidence that immune checkpoint inhibitors may work in glioblastoma and brain metastases was presented today by Dr Anna Sophie Berghoff at the ESMO Symposium on Immuno-Oncology 2014 in Geneva, Switzerland.

New model of follow up for breast cancer patients

Nov 21, 2014

Public health researchers from the University of Adelaide have evaluated international breast cancer guidelines, finding that there is potential to improve surveillance of breast cancer survivors from both a patient and health ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.