Bird flu vaccine not effective in trial

Feb 17, 2006
Bird Flu

A highly anticipated bird flu vaccine trial in Australia has proven protective for only a small minority of the 400 volunteers in the clinical trial.

Andrew Cuthbertson, the chief scientific officer of the vaccine manufacturer CSL Ltd., said about half who received the highest dose of the vaccine had an immune response comparable to that for regular human flu shots, reported the Sydney Morning Herald Friday.

Those in the trial who received single or smaller doses of the H5N1 bird flu antigen had a response below the threshold for licensing human flu vaccines. However, those receiving the vaccine had no adverse reactions beyond soreness at the injection site.

Cuthbertson said the comparison with ordinary human flu shots was "conservative" and if the deadly strain of bird flu H5N1 mutated to readily infect humans the required dose needed might be different.

CSL will begin a larger trial including children and the elderly who will receive a larger dose of the vaccine, according to Cuthbertson.

Copyright 2006 by United Press International

Explore further: A two generation lens: Current state policies fail to support families with young children

add to favorites email to friend print save as pdf

Related Stories

Panel backs sharing studies of lab-made bird flu

Mar 30, 2012

(AP) -- The U.S. government's biosecurity advisers said Friday they support publishing research studies showing how scientists made new easy-to-spread forms of bird flu because the studies, now revised, don't reveal details ...

Controversial 'bird flu' edits move ahead

Dec 22, 2011

Top US scientists on Wednesday defended their bid to stop details of a mutant bird flu virus from being published and called for global cooperation to ward off an uncontrollable pandemic.

WHO announces deal on sharing flu virus samples

Apr 17, 2011

The World Health Organisation said Saturday an agreement has been reached on sharing flu virus samples, hammered out after intense negotiations by a group on preparations for flu pandemics.

Universal flu vaccine study yields success in mice

Feb 18, 2011

(PhysOrg.com) -- Adelaide researchers have taken a step closer to the development of a universal flu vaccine, with results of a recent study showing that a vaccine delivered by a simple nasal spray could provide ...

Cell-based flu shot beats current vaccine: study

Feb 15, 2011

Flu vaccines made from lab-grown cells work at least as well as those derived from viruses cultivated in chicken eggs, the preferred method for 50 years, according to a study released Wednesday.

Recommended for you

New hadrosaur noses into spotlight

Sep 19, 2014

Call it the Jimmy Durante of dinosaurs – a newly discovered hadrosaur with a truly distinctive nasal profile. The new dinosaur, named Rhinorex condrupus by paleontologists from North Carolina State Univer ...

Scholar tracks the changing world of gay sexuality

Sep 19, 2014

With same-sex marriage now legalized in 19 states and laws making it impossible to ban homosexuals from serving in the military, gay, lesbian and bisexual people are now enjoying more freedoms and rights than ever before.

User comments : 0