Disease resistance may be genetic

Aug 30, 2007

According to a study in Evolution, resistance to certain infectious diseases may be passed genetically from parent to child. The genetic resistance may be beneficial to families as those with the gene are both unlikely to suffer from disease and unlikely to carry the disease home. Paul Schliekelman, author of the study, says the research was inspired by personal experience after catching stomach flus from his daughter three times over a six-month period.

Schliekelman used mathematical models to calculate the possible effect of “kin selection” on natural evolution. “Natural selection is typically seen as ‘survival of the fittest’, but in this case it might be more accurate to say ‘survival of the fittest families,’” says Schliekelman.

His research led to the following conclusions:

-There exists a strong tendency to catch infectious diseases from family members.

-If a relative has a gene that gives resistance to a disease, it would benefit other relatives because they would be less likely to catch the disease.

-Genes that offer resistance to infectious diseases will tend to cluster in families.

-Therefore, the resistance genes in a family help each other out and natural selection in their favor can be dramatically increased.

This model may prove useful in understanding the spread of deadly diseases and may alter the long-term natural selection of certain genes in a population. Studying the genetic behavior of these diseases could be an important step towards understanding the evolutionary history of infectious disease resistance.

Source: Blackwell Publishing

Explore further: Science of romantic relationships includes gene factor

add to favorites email to friend print save as pdf

Related Stories

Viruses impaired if their targets have diverse genes

Nov 18, 2014

When a viral infection spread through five genetically identical mice in a row, the virus replicated faster and became more virulent or severe. But when the infection spread one-by-one through five genetically ...

Three new ornamental dogwoods introduced

Nov 17, 2014

In the nursery and landscape industries, flowering dogwood (Cornus florida), kousa dogwood (Cornus kousa), and their hybrids are the most popular and economically significant members of the genus Cornus. ...

Bacteria become 'genomic tape recorders'

Nov 13, 2014

MIT engineers have transformed the genome of the bacterium E. coli into a long-term storage device for memory. They envision that this stable, erasable, and easy-to-retrieve memory will be well suited for ap ...

Recommended for you

Science of romantic relationships includes gene factor

Nov 23, 2014

(Medical Xpress)—Adolescents worry about passing tests, winning games, lost phones, fractured bones—and whether or not they will ever really fall in love. Three Chinese researchers have focused on that ...

Stress reaction may be in your dad's DNA, study finds

Nov 21, 2014

Stress in this generation could mean resilience in the next, a new study suggests. Male mice subjected to unpredictable stressors produced offspring that showed more flexible coping strategies when under ...

More genetic clues found in a severe food allergy

Nov 21, 2014

Scientists have identified four new genes associated with the severe food allergy eosinophilic esophagitis (EoE). Because the genes appear to have roles in other allergic diseases and in inflammation, the ...

Brain-dwelling worm in UK man's head sequenced

Nov 20, 2014

For the first time, the genome of a rarely seen tapeworm has been sequenced. The genetic information of this invasive parasite, which lived for four years in a UK resident's brain, offers new opportunities ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.