Research paves path for hybrid nano-materials that could replace human tissue or today's pills

November 21, 2013

A team of researchers has uncovered critical information that could help scientists understand how protein polymers interact with other self-assembling biopolymers. The research helps explain naturally occurring nano-material within cells and could one day lead to engineered bio-composites for drug delivery, artificial tissue, bio-sensing, or cancer diagnosis.

Results of this study, "Bionanocomposites: Differential Effects of Cellulose Nanocrystals on Protein Diblock Copolymers," were recently published in the American Chemical Society's BioMacromolecules. The findings were the result of a collaborative research project from the Polytechnic Institute of New York University (NYU-Poly) Montclare Lab for Protein Engineering and Molecular Design under the direction of Associate Professor of Chemical and Biomolecular Engineering Jin K. Montclare.

Bionanocomposites provide a singular area of research that incorporates biology, chemistry, materials science, engineering, and nanotechnology. Medical researchers believe they hold particular promise because—unlike the materials that build today's medical implants, for example—they are biodegradable and biocompatible, not subject to rejection by the body's immune defenses. As biocomposites rarely exist isolated from other substances in nature, scientists do not yet understand how they interact with other materials such as lipids, nucleic acids, or other organic materials and on a molecular level. This study, which explored the ways in which protein polymers interact with another biopolymer, cellulose, provides the key to better understanding how biocomposite materials would interact with the human body for .

The materials analyzed were composed of bioengineered protein polymers and cellulose nanocrystals and hold promise for medical applications including non-toxic, targeted systems. Such bionanocomposites could also be used as scaffolding for tissue growth, synthetic biomaterials, or an environmentally friendly replacement for petroleum-derived polymers currently in use.

Explore further: Molecularly imprinted polymers and bio-engineering

More information:

Related Stories

Nanotech drug smugglers

November 12, 2013

Tiny capsules of carbon are invisible to the chemical gatekeeper that flushes potentially harmful substances out of our bodies' cells, according to research published in the International Journal of Computational Biology ...

Recommended for you

Moonlighting molecules: Finding new uses for old enzymes

November 27, 2015

A collaboration between the University of Cambridge and MedImmune, the global biologics research and development arm of AstraZeneca, has led researchers to identify a potentially significant new application for a well-known ...

A new form of real gold, almost as light as air

November 25, 2015

Researchers at ETH Zurich have created a new type of foam made of real gold. It is the lightest form ever produced of the precious metal: a thousand times lighter than its conventional form and yet it is nearly impossible ...

Getting under the skin of a medieval mystery

November 23, 2015

A simple PVC eraser has helped an international team of scientists led by bioarchaeologists at the University of York to resolve the mystery surrounding the tissue-thin parchment used by medieval scribes to produce the first ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.