Drug technology to improve health care

July 2, 2013
Drug technology to improve health care
The construction and release of bioactive molecules from the porphyrin-based yoctowells.

Researchers at RMIT University are developing new generation nano-sized drug delivery technology.

Dr Sheshanath Bhosale from RMIT's School of Applied Sciences is collaborating with scientists from the Indian Institute of Chemical Technology in Hyderabad on the multi-disciplinary research project.

Dr Bhosale and his team are analysing the effectiveness of the of a bioactive molecule from yoctowells - novel surface-engineered molecular cavities which allow the analysis of the separation, containment and manipulation of individual molecules.

"What is exciting is that the yoctowells system manipulates guest molecules, which means there is great potential to radically change the practice of therapy for a variety of diseases and disorders," he said.

"The yoctowells system therefore presents an excellent starting point for a new approach for encapsulation of drugs and sustained and controlled drug release and provides a platform for more sophisticated designs in the future."

Controlled technology represents one of the frontier areas of science and the development of nano-sized to transport drugs to will enable highly targeted treatments to become available for conventional use.

This offers numerous advantages compared to conventional dosage forms, enhancing the drug release profile through absorption, distribution and elimination and improving product efficacy and safety, as well as patient convenience and compliance.

The research was published in the June edition of Scientific Reports, a primary from the publishers of Nature, covering all areas of the natural sciences.

Professor Matthew Cuthbertson, Deputy Pro Vice-Chancellor Research and Innovation in the College of Science, Engineering and Health, said the publication was an example of RMIT's commitment to high-quality research of national and international significance.

"This study demonstrates that researchers at RMIT use theoretical and practical know-how to create innovative solutions to transform the future in the world of medicine," he said.

"In particular, this type of research represents a significant advance in the development of novel ways of administering protein and gene therapeutics to patients and contributes to advancements in the field of nano-biotechnology."

Explore further: Fabrication of new elastic 'soft capsule' using nano-sized flakes

Related Stories

Slow-release 'jelly' delivers peptide drugs better

January 28, 2013

Duke University biomedical engineers have developed a new delivery system that overcomes the shortcomings of a promising class of peptide drugs – very small proteins – for treating diseases such as diabetes and cancer.

Nanoparticles for controlled drug release

June 13, 2013

Scientists from CIC bioGUNE and the Laboratoire de Chimie des Polymères Organiques (LCPO) in Bordeaux have jointly undertaken a project to develop "smart" nanoparticles. These polymeric particles act as "nanomissiles" against ...

Recommended for you

Electrical circuit made of gel can repair itself

August 25, 2015

(Phys.org)—Scientists have fabricated a flexible electrical circuit that, when cut into two pieces, can repair itself and fully restore its original conductivity. The circuit is made of a new gel that possesses a combination ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.