Developing test for disease-carrying `Trojan cows'

Jun 12, 2013

University of Adelaide researchers are developing a test to help eliminate hidden carriers of a significant disease in Australian cattle herds, commonly known as Bovine Pestivirus.

It's estimated that as many as 91.5% of Australian dairy and herds, and just over half of all cattle, have been exposed to Bovine Pestivirus, more correctly called Bovine Viral (BVD).

While most normally healthy cattle recover easily from the disease, up to 17% of South Australian are believed to contain at least one persistently infected 'carrier' animal.

Sasha Lanyon, PhD student, says many farmers are unaware that their herds are infected with BVD infection and that it is costing them money.

"BVD is a reproductive disease," she says. "Cows can abort or have stillborn , or the calves can be infected with the disease while still in the womb. These calves become persistently infected 'carriers' which can never be cured and go on to infect others."

"The disease can also cause substantial losses through leading to higher rates of other major cattle diseases such as mastitis."

Although there are reliable available that can detect persistently infected animals, they can't identify cows that are carrying an infected .

"These so-called 'Trojan cows' give birth to persistently infected calves which can cause serious loss to herds they are introduced to," says Ms Lanyon.

"One South Australian herd lost nearly $150,000 in 2008 when a persistently infected bull carrying the virus was introduced to the herd, which had never been exposed to the disease before."

Ms Lanyon, under the supervision of Professor of Veterinary Epidemiology Michael Reichel, is conducting a pilot trial in a small group of heifers carrying infected calves and, if successful, will continue with a full-scale trial next year. Preliminary results are promising.

"We're aiming to be able to detect low levels of virus in the cow during late gestation when the virus in the infected foetus crosses over the placenta," she says.

"The ability to identify cows with infected foetuses would minimise the threat of these 'Trojan cows' and be a very valuable tool in BVD control and eradication."

Ms Lanyon has just presented her research at the World Association of Veterinary Laboratory Diagnosticians conference in Berlin, the premier conference in the field.

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