Scientists peer into a cell in real time

May 31, 2013 by Bill Hathaway
Research in the News: Yale scientists peer into a cell in real time

A dream of scientists has been to visualize details of structures within our cells in real time, a breakthrough that would greatly aid in the study of their function. However, even the best of current microscopes can take minutes to recreate images of the internal machinery of cells at a usable resolution.

Thanks to a technical tour de force, Yale University researchers can now generate accurate images of sub- in milliseconds rather than minutes.

This image of microtubules, which act as a cellular scaffolding, was captured in just 33 milliseconds. "We can now see research come to life and tackle complex questions or conditions which require hundreds of images, something we have not been able to do before," said Joerg Bewersdorf, assistant professor of and biomedical engineering and senior author of the research, published in the journal Nature Methods.

To learn more about video-rate nanoscopy, see www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.2488.html

Explore further: Bringing life into focus

add to favorites email to friend print save as pdf

Related Stories

Virtual nanoscopy: Like 'Google Earth' for cell biologists

Aug 06, 2012

Just as users of Google Earth can zoom in from space to a view of their own backyard, researchers can now navigate biological tissues from a whole embryo down to its subcellular structures thanks to recent advances in electron ...

Bringing life into focus

May 17, 2013

Spinning-disk confocal microscopy is an optical imaging technique that can be used to generate detailed three-dimensional fluorescence images of living cells and their contents. Although a powerful tool for ...

Recommended for you

For resetting circadian rhythms, neural cooperation is key

9 hours ago

Fruit flies are pretty predictable when it comes to scheduling their days, with peaks of activity at dawn and dusk and rest times in between. Now, researchers reporting in the Cell Press journal Cell Reports on April 17th h ...

Rapid and accurate mRNA detection in plant tissues

10 hours ago

Gene expression is the process whereby the genetic information of DNA is used to manufacture functional products, such as proteins, which have numerous different functions in living organisms. Messenger RNA (mRNA) serves ...

For cells, internal stress leads to unique shapes

Apr 16, 2014

From far away, the top of a leaf looks like one seamless surface; however, up close, that smooth exterior is actually made up of a patchwork of cells in a variety of shapes and sizes. Interested in how these ...

User comments : 0

More news stories

Deadly human pathogen Cryptococcus fully sequenced

Within each strand of DNA lies the blueprint for building an organism, along with the keys to its evolution and survival. These genetic instructions can give valuable insight into why pathogens like Cryptococcus ne ...

Better thermal-imaging lens from waste sulfur

Sulfur left over from refining fossil fuels can be transformed into cheap, lightweight, plastic lenses for infrared devices, including night-vision goggles, a University of Arizona-led international team ...

Hackathon team's GoogolPlex gives Siri extra powers

(Phys.org) —Four freshmen at the University of Pennsylvania have taken Apple's personal assistant Siri to behave as a graduate-level executive assistant which, when asked, is capable of adjusting the temperature ...