Scientists peer into a cell in real time

May 31, 2013 by Bill Hathaway
Research in the News: Yale scientists peer into a cell in real time

A dream of scientists has been to visualize details of structures within our cells in real time, a breakthrough that would greatly aid in the study of their function. However, even the best of current microscopes can take minutes to recreate images of the internal machinery of cells at a usable resolution.

Thanks to a technical tour de force, Yale University researchers can now generate accurate images of sub- in milliseconds rather than minutes.

This image of microtubules, which act as a cellular scaffolding, was captured in just 33 milliseconds. "We can now see research come to life and tackle complex questions or conditions which require hundreds of images, something we have not been able to do before," said Joerg Bewersdorf, assistant professor of and biomedical engineering and senior author of the research, published in the journal Nature Methods.

To learn more about video-rate nanoscopy, see www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.2488.html

Explore further: Researchers discover new mechanism of DNA repair

Related Stories

Virtual nanoscopy: Like 'Google Earth' for cell biologists

Aug 06, 2012

Just as users of Google Earth can zoom in from space to a view of their own backyard, researchers can now navigate biological tissues from a whole embryo down to its subcellular structures thanks to recent advances in electron ...

Bringing life into focus

May 17, 2013

Spinning-disk confocal microscopy is an optical imaging technique that can be used to generate detailed three-dimensional fluorescence images of living cells and their contents. Although a powerful tool for ...

Recommended for you

Researchers discover new mechanism of DNA repair

11 hours ago

The DNA molecule is chemically unstable giving rise to DNA lesions of different nature. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are needed.

Stopping Candida in its tracks

Jul 03, 2015

Scientists are one step closer to understanding how a normally harmless fungus changes to become a deadly infectious agent.

New technique maps elusive chemical markers on proteins

Jul 02, 2015

Unveiling how the 20,000 or so proteins in the human body work—and malfunction—is the key to understanding much of health and disease. Now, Salk researchers developed a new technique that allows scientists ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.