Formation of functionalized nanowires by control of self-assembly using multiple modified amyloid peptides

May 27, 2013
Formation of functionalized nanowires by control of self-assembly of modified amyloid peptides"

Researchers in Japan and US have developed a new technique for efficiently creating functionalized nanowires for the first time ever.

Prof. Sakaguchi and his team in Graduate School of Science, Hokkaido University,jointly with MANA PI Prof. Kohei Uosaki and a research group from the University of California, Santa Barbara, have successfully developed a new technique for efficiently creating functionalized nanowires for the first time ever.

The group focused on the natural propensity of amyloid peptides, molecules which are thought to cause Alzheimer's disease, to self-assemble into nanowires in an and controlled this molecular property to achieve their feat.

Functionalized nanowires are extremely important in the construction of nanodevices because they hold promise for use as and for the generation of novel properties, such as conductivity, catalysts and which are derived from their fine structure. However, some have remarked on the technical and financial limitations of the microfabrication technology required to create these structures. Meanwhile, molecular self-organization and functionalization have attracted attention in the field of next-generation nanotechnology development. Amyloid , which are thought to cause Alzheimer's disease, possess the ability to self-assemble into highly stable in an aqueous solution. Focusing on this, the research team became the first to successfully develop a new method for efficiently creating a multifunctional nanowire by controlling this molecular property.

The team designed a new peptide called SCAP, or structure-controllable amyloid peptide, terminated with a three-amino-acid-residue cap. By combining multiple SCAPs with different caps, the team found that self-organization is highly controlled at the molecular level. Using this new control method, the team formed a molecular nanowire with the largest aspect ratio ever achieved. In addition, they made modifications using various functional molecules including metals, semiconductors and biomolecules that successfully produced an extremely high quality functionalized nanowire. Going forward, this method is expected to contribute significantly to the development of new through its application to a wide range of functional nanomaterials with self-organizing properties.

Explore further: Development of world’s first functional polymer nanowire fabrication technology by pulsed laser irradiation

Related Stories

New nanowire transistors may help keep Moore's Law alive

May 2, 2013

(Phys.org) —Two French researchers, Guilhem Larrieu and Xiang‑Lei Han, may have succeeded in possibly setting back the date to which Moore's Law would no longer apply by creating a new kind of nanowire Field-Effect Transistor ...

Recommended for you

New nanomaterial maintains conductivity in 3-D

September 4, 2015

An international team of scientists has developed what may be the first one-step process for making seamless carbon-based nanomaterials that possess superior thermal, electrical and mechanical properties in three dimensions.

Graphene made superconductive by doping with lithium atoms

September 2, 2015

(Phys.org)—A team of researchers from Germany and Canada has found a way to make graphene superconductive—by doping it with lithium atoms. In their paper they have uploaded to the preprint server arXiv, the team describes ...

Making nanowires from protein and DNA

September 3, 2015

The ability to custom design biological materials such as protein and DNA opens up technological possibilities that were unimaginable just a few decades ago. For example, synthetic structures made of DNA could one day be ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.