(PhysOrg.com) -- Exactly 150 years after the first color photograph was produced, scientists have devised a way of employing the full spectrum of colors from synchrotron and free-electron laser x radiation to image nanometer-sized subjects with unprecedented clarity and speed, and in three dimensions. This new research technique is expected to improve imaging on the nanoscale in the quest for advances in pharmaceutical development and new materials for next-generation technologies.
The researchers, from the ARC Centre of Excellence for Coherent X-ray Science (The University of Melbourne and La Trobe University), SLAC National Accelerator Laboratory, and Argonne National Laboratory used the Argonne X-ray Science Division (XSD) 2-ID-B x-ray beamline at the U.S. Department of Energy Office of Sciences Advanced Photon Source (APS) to develop this new technique, dubbed polyCDI.
PolyCDI extends the capabilities of coherent diffractive imaging (CDI), a lens-less imaging technique that has been a mainstay for experiments observing matter on the scale of x-ray wavelengths.
But CDI has its limits. Even though the light from synchrotron x-rays produced at facilities like the APS is the brightest available for research, it is not bright enough to capture precise images at the nanoscale even if exposures are very long, and it cannot be used to capture movies of chemical processes, biological changes, and the transformation of materials under stress.
PolyCDI promises to change the game for diffractive imaging. Rather than employing a single wavelength of light from a high-brightness x-ray source such as the APS, polyCDI utilizes broadband light, also available from the APS, that contains many wavelengths at the same time. The results of the groups research, just published in Nature Photonics, show that polyCDI can produce images almost two orders of magnitude faster than conventional CDI.
Deployed in concert with a new generation of fast x-ray detectors, CDI could make possible the first time-resolved nano-movies of changes to materials brought on by extreme temperatures or high magnetic fields, processes that are vital in developing advanced materials for new technologies. Coupled to innovative focusing optics, polyCDI could greatly reduce the time needed to gather information about the composition of diseased cells.
Professor Keith Nugent, of the University of Melbourne and a member of the polyCDI team, called the discovery an exciting development. Typically for best imaging, researchers need to convert samples to crystals, but this is not always possible in all samples, he said. This discovery of utilizing full color synchrotron light to improve precision and speed of imaging has huge potential.
Ian McNulty, of XSD and a collaborator on the work, said, "By going 'broadband' this new capability stands to revolutionize x-ray imaging much as the advent of broadband communications technology has changed our lives. We are especially excited about applying it to CDI with higher energy x-rays to peer deeper into dense materials, ultimately to see features on the scale of single atoms."
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More information: Brian Abbey, et al. , Lensless imaging using broadband X-ray sources, Nat. Photo. 5, 420 (published online July 2011). DOI:10.1038/NPHOTON.2011.125