NIH stops study of niacin to prevent heart attacks

May 26, 2011 By LAURAN NEERGAARD , AP Medical Writer

(AP) -- Disappointing news: A drug that raises people's so-called good cholesterol didn't go on to prevent heart attacks.

The National Institutes of Health halted a major study of high-dose niacin, a type of B vitamin, on Thursday because the drug wasn't fighting heart disease after all. It was the latest setback in the quest to harness to fight the bad kind.

LDL cholesterol is the main source of artery clogs. Popular , sold under such names as Zocor and Lipitor, are mainstays in lowering LDL. Yet many statin users still suffer heart attacks. So scientists are testing if adding different kinds of drugs to statins would increase HDL - the good kind that helps prevent blocked arteries - enough to protect the heart.

Explore further: Study finds information lacking from FDA on implanted medical devices

not rated yet
add to favorites email to friend print save as pdf

Related Stories

New drug produces steep drop in bad cholesterol

Nov 17, 2010

(AP) -- An experimental drug boosted good cholesterol so high and dropped bad cholesterol so low in a study that doctors were stunned and voiced renewed hopes for an entirely new way of preventing heart attacks ...

Gene Mutations Linked to Statin Resistance

Dec 17, 2008

(PhysOrg.com) -- Scientists at Duke University Medical Center have identified genetic mutations that may help explain why some people don't respond very well to statins, drugs taken by millions of Americans to fight high ...

Recommended for you

Justice Department says Shire will pay $56.5M fine

Sep 24, 2014

The U.S. Department of Justice said Wednesday that Irish drugmaker Shire will pay $56.5 million to settle allegations it broke the law in promoting five different drugs, including its attention deficit disorder drugs Adderall ...

New FDA label bolsters safety case for Chantix

Sep 24, 2014

New government-approved labeling on Pfizer's drug Chantix suggests that the anti-smoking medication may not carry the risks of suicidal behavior that first earned it the Food and Drug Administration's strongest warning more ...

User comments : 0