Bacteria use caffeine as food source

May 24, 2011

A new bacterium that uses caffeine for food has been discovered by a doctoral student at the University of Iowa. The bacterium uses newly discovered digestive enzymes to break down the caffeine, which allows it to live and grow.

"We have isolated a new caffeine-degrading bacterium, putida CBB5, which breaks caffeine down into carbon dioxide and ammonia," says Ryan Summers, who presents his research today at the 111th General Meeting of the American Society for Microbiology in New Orleans.

Caffeine itself is composed of carbon, nitrogen, hydrogen and oxygen, all of which are necessary for bacterial cell growth. Within the caffeine molecule are three structures, known as , composed of 1 carbon and 3 hydrogens atoms. This bacterium is able to effectively remove these methyl groups (a process known as N-demethylization) and essentially live on caffeine.

Summers and his colleagues have identified the three enzymes responsible for the N-demethylization and the genes that code for these enzymes. Further testing showed that the compounds formed during break down of caffeine are natural building blocks for drugs used to treat asthma, improve blood flow and stabilize .

Currently these pharmaceuticals are difficult to synthesize chemically. Using CBB5 enzymes would allow for easier pharmaceutical production, thus lowering their cost. Another potential application is the decaffeination of coffee and tea as an alternative to harsh chemicals currently used.

"This work, for the first time, demonstrates the enzymes and genes utilized by bacteria to live on caffeine," says Summers.

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4 comments

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EWH
5 / 5 (2) May 24, 2011
Noooo!!! Caffeine-destroying germs! Humanity would be doomed if these get out!
Eric_B
not rated yet May 24, 2011
EWH; LOL

Hmmm....just on a whim I have been putting a pinch of old coffee grounds into the water when I am rooting cuttings. I never really did a controlled study or research to see if I was helping the plant or killing it. Do cuttings like ammonia?
stealthc
not rated yet May 24, 2011
lol I wouldn't worry about that very much, you would have to produce a freak event where that specific bacteria monopolized on the situation over all others, versus the usual variety that it likely has (1000's upon 1000's of varieties of bacteria all intermingling).
Donutz
5 / 5 (1) May 24, 2011
Big deal. I've been using caffeine as a food source for years!

:-)

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