Stanford creates first PhD program in stem cell science

Apr 29, 2011 By Christopher Vaughan

Stanford University’s Faculty Senate today approved the creation of what officials believe is the first stem cell science PhD program in the nation and, perhaps, the world. The new doctoral program in stem cell biology and regenerative medicine is also the first interdisciplinary doctoral program created by the School of Medicine in recent years.

School officials say the fact that the university is taking the rare step of creating a new doctoral program acknowledges the growing importance of stem cell research in the realm of biomedical science. The senate's initial approval of the program extends for five years.

“Stem cell biology is a distinct discipline that requires unique skills and includes a scope of knowledge and a skill set that is not covered by other disciplines,” said Renee Reijo Pera, PhD, professor of obstetrics and gynecology and director of the new PhD program.

Program leaders note that Stanford is among a small number of U.S. universities that have the necessary ingredients to create a doctoral program teaching the full range of stem cell science

In particular, Stanford has received $186 million during the past five years — more than any other institution in the state — from the California Institute for Regenerative Medicine, which was established by state voters in 2004 to advance stem cell research in the face of more-restrictive federal funding policies. The funds have enabled Stanford to build facilities such as the Lorry I. Lokey Stem Cell Research Building (believed to be the largest building in the nation dedicated to stem cell research), to develop educational outreach and tissue banking capabilities, and to recruit a number of renowned researchers and trainees from whom the new PhD students can learn both the science and ethics of human stem cell research.

Philip Pizzo, MD, dean of the School of Medicine, noted that the program will draw on expertise from throughout the university to “prepare tomorrow’s leaders to make fundamental discoveries in how understanding the basic biology of can impact the study of human biology and disease." The program, he added, will also create new tools and technologies to repair and regenerate cells, organs and tissues.

"It is an exciting and rapidly changing new discipline and one where Stanford can certainly be a leader,” Pizzo said.

CIRM president Alan Trounson, PhD, said the doctoral program “is unique in its interdisciplinary nature and focus on applying discoveries to treat disease. This program, along with CIRM’s training and research support at Stanford, will prepare the next generation of scientists to become leaders in the search for new cures.”

The creation of a doctoral program will also provide a boost to graduate students and accelerate the development of the field itself. “We are establishing an entirely new field that affects both life sciences and medicine,” said Irving Weissman, MD, director of the Stanford Institute for Stem Cell Biology and Regenerative Medicine and professor of pathology. “We are doing this in a time of federal cutbacks of support for graduate students, including those doing life sciences in general and those doing medical science training. The fact that the university is opening this program now allows us to recruit those students whose primary objective is to do stem cell research and stem cell medicine. We believe this will help us establish the new field and accelerate the translation of discoveries into clinical therapies.”

Students themselves played a significant role in the inception of this program. “Incoming students were voicing frustration that the existing PhD programs were outstanding within their narrow disciplines but none provided the cross-disciplinary training required for a successful career in regenerative medicine,” said Theo Palmer, PhD, associate professor of neurosurgery and co-director of the doctoral program. “The new program not only engages subjects taught within the School of Medicine, it crosses the Stanford schools to capture fundamental principles in engineering, law, business and society.”

Reijo Pera added that the inclusion of regenerative medicine emphasizes the doctoral program’s focus on moving basic science findings from the laboratory into the clinic, making it truly “translational” in nature.

Prospective students can begin applying this fall to begin the program in the fall of 2012. The first class will be composed of three to six students, although the program will eventually enroll six students every year, for a program total of 24 students. Students will be required to take prescribed courses, pass a qualifying exam and write a dissertation. One of the distinguishing features of the PhD program is that all students will be required to undergo an immersive clinical rotation in which they will shadow attending surgeons, physicians, residents or fellows.

Reijo Pera said the PhD program in stem cell biology and will appeal strongly to a new generation of graduate students who are deeply interested in applying their discoveries. “Students used to be content simply studying the basic biological sciences, but a lot of them now want to bring that work forward to address critical clinical needs,” she said. “They are interested in changing the world.”

Explore further: Model uncovers malaria parasite causes red blood cell changes

Related Stories

UCLA gets $3.75M stem cell research grant

Sep 14, 2005

The UCLA Institute for Stem Cell Biology and Medicine has received a three-year, $3.75-million grant to train scientists to conduct stem cell research.

Humans more diverse than we allow

Mar 29, 2011

A question central to Gillian Einstein's research is, How can I do science that would not make essentialist assumptions about the body?

Adult kidney stem cells found in fish

Jan 26, 2011

( -- It has long been a given that adult humans -- and mammals in general -- lack the capacity to grow new nephrons, the kidney?s delicate blood filtering tubules, which has meant that dialysis, and ultimately ...

Setting his sights on a cure

Jan 11, 2011

For poets and lovers, the eyes are windows to the soul. But for researchers like Dr. Henry Klassen, they provide unparalleled access to the central nervous system.

Recommended for you

A CRISPR antiviral tool

3 hours ago

Emory scientists have adapted an antiviral enzyme from bacteria called Cas9 into an instrument for inhibiting hepatitis C virus in human cells.

Chromosome-folding theory shows promise

4 hours ago

Human chromosomes are much bigger and more complex than proteins, but like proteins, they appear to fold and unfold in an orderly process as they carry out their functions in cells.

New 3-D method improves the study of proteins

Apr 27, 2015

Researchers have developed a new computational method called AGGRESCAN3D which will allow studying the 3D structure of folded globular proteins and substantially improve the prediction of any propensity for ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.