Blueberries may inhibit development of fat cells

Apr 10, 2011

The benefits of blueberry consumption have been demonstrated in several nutrition studies, more specifically the cardio-protective benefits derived from their high polyphenol content. Blueberries have shown potential to have a positive effect on everything from aging to metabolic syndrome.

Recently, a researcher from Texas Woman's University (TWU) in Denton, TX, examined whether could play a role in reducing one of the world's greatest health challenges: obesity. Shiwani Moghe, MS, a graduate student at TWU, decided to evaluate whether blueberry polyphenols play a role in adipocyte differentiation, the process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal cell specialized for the synthesis and storage of fat. Plant polyphenols have been shown to fight adipogenesis, which is the development of , and induce lipolysis, which is the breakdown of lipids/fat. Moghe will present her research at the Experimental Biology 2011 meeting for the American Society for Nutrition on Sunday, April 10.

"I wanted to see if using blueberry polyphenols could inhibit obesity at a molecular stage," said Moghe. The study was performed in tissue cultures taken from mice. The polyphenols showed a dose-dependent suppression of adipocyte differentiation. The content in the control group was significantly higher than the content of the tissue given three doses of blueberry polyphenols. The highest dose of blueberry polyphenols yielded a 73% decrease in lipids; the lowest dose showed a 27% decrease.

"We still need to test this dose in humans, to make sure there are no adverse effects, and to see if the doses are as effective. This is a burgeoning area of research. Determining the best dose for humans will be important," said Moghe. "The promise is there for blueberries to help reduce adipose tissue from forming in the body."

These preliminary results contribute more items to the laundry list of benefits related to blueberries, which have already been shown to mitigate health conditions like cardiovascular disease and .

Explore further: NYSCF Research Institute announces largest-ever stem cell repository

add to favorites email to friend print save as pdf

Related Stories

Blueberry ameliorates hepatic fibrosis

Jun 17, 2010

A research team from China examined the effect of blueberry on hepatic fibrosis and detoxification enzyme systems in rats. The results demonstrated that blueberry has a therapeutic effect on CCl4-induced hepatic fibrosis ...

Purple pigments and obesity

Feb 11, 2008

Scientists in Arkansas are reporting new evidence that natural pigments responsible for the beautiful blue/purple/reddish color of certain fruits and vegetables may help prevent obesity. Their animal study, ...

Recommended for you

YEATS protein potential therapeutic target for cancer

18 hours ago

Federal Express and UPS are no match for the human body when it comes to distribution. There exists in cancer biology an impressive packaging and delivery system that influences whether your body will develop cancer or not.

Precise and programmable biological circuits

19 hours ago

A team led by ETH professor Yaakov Benenson has developed several new components for biological circuits. These components are key building blocks for constructing precisely functioning and programmable bio-computers.

User comments : 0