Thailand developing dengue vaccine: researcher

Feb 22, 2011

Researchers in Thailand say they have developed a prototype vaccine against dengue fever and will conduct further tests with the aim of bringing it to market within a decade.

The vaccine against the mosquito-borne disease was jointly developed by scientists from Thailand's Chiang Mai University, Mahidol University and the government's National Centre for Genetic Engineering and Biotechnology.

"It's the first time in Thailand that we created a prototype vaccine against dengue that has the attributes we wanted," said Associate Professor Nopporn Sithisombat at Chiang Mai University in northern Thailand.

"Our goal is to create a vaccine against dengue fever in children" said Nopporn.

The vaccine has been tested on mice and monkeys. The next stage will be human trials, he said.

Dengue, for which there is no known treatment, causes a severe flu-like illness for most victims that lasts about a week. There are four strains, one of which is potentially lethal.

The Thai team said it had created a hybrid that carries of all four types.

The developers have struck a licensing agreement with Thai biotech firm BioNet-Asia, which will further develop the vaccine with the aim of releasing the first commercial batch within 10 years, Nopporn said.

Other researchers appear ahead in the race: Sanofi Pasteur, the vaccines division of French drugmaker Sanofi-Aventis, announced in November that its dengue was in the final stage of clinical development.

In Thailand more than 115,000 people were infected and 141 died last year from dengue fever, many of them young people, according to the government.

Explore further: FDA OKs Cubist antibiotic for serious infections

add to favorites email to friend print save as pdf

Related Stories

China alerts about dengue fever

Oct 11, 2006

China has issued an alert against dengue fever as the peak season for the mosquito-borne disease continues in the southern parts of the country.

Scientists closing the zap on dengue fever

Jan 01, 2009

(PhysOrg.com) -- A mosquito-borne virus that each year harms up to 100 million people and kills more than 20,000 is a step closer to being controlled after a breakthrough by Queensland scientists.

Study: Dengue fever is underreported

Oct 16, 2007

The American Society of Tropical Medicine and Hygiene is concerned about the U.S. blood supply due to underreporting of dengue fever.

US researchers hopeful for dengue vaccine

Feb 17, 2011

Promising advances have been made in the testing of possible vaccines to prevent the mosquito-borne dengue virus, which kills 25,000 people every year, researchers said Thursday.

Recommended for you

FDA OKs Cubist antibiotic for serious infections

Dec 20, 2014

The Food and Drug Administration has approved a new medicine to fight complex infections in the abdomen and urinary tract, the fourth antibiotic the agency has approved since May.

Xtoro approved for swimmer's ear

Dec 18, 2014

(HealthDay)—Xtoro (finafloxacin otic suspension) eardrops have been approved by the U.S. Food and Drug Administration to treat swimmer's ear, clinically known as acute otitis externa.

Drug interaction identified for ondansetron, tramadol

Dec 18, 2014

(HealthDay)—In the early postoperative period, ondansetron is associated with increased requirements for tramadol consumption, according to a review and meta-analysis published online Dec. 10 in Anaesthesia.

New system targets germs in donated blood plasma

Dec 17, 2014

(HealthDay)—A new system designed to eliminate germs in donated blood plasma and reduce the risk of transmitting a plasma-borne infection has been approved by the U.S. Food and Drug Administration.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.