Menopausal hot flashes may be a good sign for heart

"While they are certainly bothersome, hot flashes may not be all bad," said Northwestern Medicine endocrinologist Emily Szmuilowicz, MD, who is lead author of the study. "Our research found that despite previous reports suggesting that menopause symptoms were associated with increased levels of risk markers for heart disease, such as blood pressure and cholesterol, the actual outcomes tell a different story."

Szmuilowicz, who co-chaired the study along with JoAnn Manson, MD, DrPH, and Ellen Seely, MD from Harvard Medical School, reviewed medical information from 60,000 women who were enrolled in the Women's Health Initiative Observational Study and followed for ten years, to determine the relationship between menopause symptoms and cardiovascular events. Subjects were grouped into four categories – women who experienced hot flashes and night sweats at the onset of menopause, later in menopause, during both time periods, and not at all.

"We found that women who experienced symptoms when they began menopause had fewer cardiovascular events than those who experienced hot flashes late in menopause or not at all," said Szmuilowicz.

The results are significant since there has been concern that menopausal symptoms, which result from instability in the blood vessels in the skin, may put women at risk for other types of vascular problems as well.

"It is reassuring that these symptoms, which are experienced by so many women, do not seem to correlate with increased risk of cardiovascular disease," said Szmuilowicz.

Szmuilowicz and team say more research needs to be done in order to understand the mechanisms behind the association, but say it's good news for the millions of women who experience these troublesome symptoms at the time of menopause.

"Hot flashes will never be enjoyable, but perhaps these findings will make them more tolerable," said Szmuilowicz.

More information: The paper titled "Vasomotor symptoms and cardiovascular events in postmenopausal women" is now available online and will be printed in the June issue of Menopause. http://journals.lw … default.aspx

Provided by Northwestern Memorial Hospital