Mayo Clinic determines lifetime risk of adult rheumatoid arthritis

Jan 05, 2011

Mayo Clinic researchers have determined the lifetime risk of developing rheumatoid arthritis and six other autoimmune rheumatic diseases for both men and women. The findings appear online in Arthritis and Rheumatism.

"We estimated the lifetime risk for rheumatic disease for both sexes, something that had not been done before -- separately or collectively," says Cynthia Crowson Mayo Clinic biostatistician and first author. "Prevalence and incidence rates existed, but prevalence figures underestimate individual risk and incidence rates express only a yearly estimate."

The researchers were looking for an accurate basis to offer an easy-to-understand average risk over a person's lifetime, knowing that risk changes at almost every age. They used data from the Rochester Epidemiology Project, a long-term epidemiology resource based on patients in Olmsted County, Minn. The cohort of 1179, consisted of patients diagnosed between 1955 and 2007, allowed the team to extrapolate the nationwide estimates.

The adult lifetime risk in the United States of having some kind of inflammatory autoimmune disease is 8.4 percent for women and 5.1 percent for men. Based on year 2000 population figures, that means one woman in 12 and one man in 20 will develop one of the conditions in their lifetime. The authors consider that a substantial risk and say their findings should encourage more research on the value of early diagnosis and intervention for people with increased of arthritis. They hope the new figures will help in counseling patients and in fundraising efforts to find improved treatments.

The figures below reflect for the respective diseases, based on the Mayo findings.

 Disease   Women
 Men 
(RA) 3.6% or 1 in 28  1.7% or 1 in 59 
Polymyalgia Rheumatica 2.4%1.7%
Systemic Lupus Erythematosus .9% .2%
Giant Cell Arteritis 1% .5%
Psoriatic Arthritis .5% .6%
Primary Sjögrens syndrome .8% .04%
Ankylosing Spondylitis .1% .6%

Explore further: Flu season, early again, hitting hard in South and Midwest

add to favorites email to friend print save as pdf

Related Stories

Rheumatoid arthritis rising among women

Oct 26, 2008

After four decades on the decline, rheumatoid arthritis is on the upswing among women in the United States. That's the finding presented by Mayo Clinic investigators at the annual meeting of the American College of Rheumatology/Association ...

Rheumatoid arthritis incidence on the rise in women

May 26, 2010

The incidence of rheumatoid arthritis (RA) in women has risen during the period of 1995 to 2007, according to a newly published study by researchers from the Mayo Clinic. This rise in RA follows a 4-decade period of decline ...

New insights into chronic inflammation and atherosclerosis

May 25, 2007

[B]Inflammatory rheumatic disease and smoking independently predict aortic inflammation, suggests study of coronary artery surgery survivors[/B] Rheumatoid arthritis, lupus, and other inflammatory rheumatic diseases are ...

Recommended for you

Liberia holds Senate vote amid Ebola fears

1 hour ago

Health workers manned polling stations across Liberia on Saturday as voters cast their ballots in a twice-delayed Senate vote that has been criticized for its potential to spread the deadly Ebola disease.

Evidence-based recs issued for systemic care in psoriasis

21 hours ago

(HealthDay)—For appropriately selected patients with psoriasis, combining biologics with other systemic treatments, including phototherapy, oral medications, or other biologic, may result in greater efficacy ...

Bacteria in caramel apples kills at least four in US

21 hours ago

A listeria outbreak believed to originate from commercially packaged caramel apples has killed at least four people in the United States and sickened 28 people since November, officials said Friday.

Steroid-based treatment may answer needs of pediatric EoE patients

22 hours ago

A new formulation of oral budesonide suspension, a steroid-based treatment, is safe and effective in treating pediatric patients with eosinophilic esophagitis (EoE), according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal ...

Discovery of genes that predispose a severe form of COPD

Dec 19, 2014

A study by Ramcés Falfán-Valencia, researcher at the National Institute of Respiratory Diseases (INER), found that the mestizo Mexican population has a number of variations in certain genes that predispose ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.