Preterm infants may need a boost

Dec 01, 2010

A new study suggests that preterm infants may not be fully protected against invasitve pneumococcal disease under the current United Kingdom immunization schedule. The findings are reported in the November issue of the journal Clinical and Vaccine Immunology.

The study, conducted by researchers from Newcastle University, began with a survey of UK units. The survey found that preterm infants at increased risk of invasive pneumococcal disease were not being adequately immunized because of a lack of evidance that these infants are protected by the pneumococcal conjugate vaccine.

have significantly less maternally derived antibody than full-term infants. Early effective immunization is therefore especially important to decrease the chances of pneumococcal infection.

"Our study found that in addition to a poor response to serotype 6B, perterm infants had a diminished response to serotype 23F, and several infants remained unprotected to at least one serotype following a booster dose of the vaccine," says Samantha Moss, an author of the report. "These results support the need for a booster dose in the second year of life."

Current vaccination schedules in the UK calls for immunization at 2, 4, and 13 months. Evidence suggests that are more likely to remain unprotected following the initial immunization and would therefore benefit from increased monitoring post-primary immunization and, if they are unprotected, to offer them an early booster dose.

Explore further: Discovery of genes that predispose a severe form of COPD

Provided by American Society for Microbiology

not rated yet
add to favorites email to friend print save as pdf

Related Stories

British infants to get meningitis vaccine

Aug 28, 2006

British health officials are beginning an immunization program designed to prevent infants and young children from contacting meningitis and septicemia.

SIDS link: Low blood pressure in preterm infants

Dec 08, 2008

Scientists from Monash University, Melbourne have shown that infants born prematurely have lower blood pressure during sleep in the first six months of life, compared to healthy, full-term infants.

Recommended for you

Discovery of genes that predispose a severe form of COPD

1 hour ago

A study by Ramcés Falfán-Valencia, researcher at the National Institute of Respiratory Diseases (INER), found that the mestizo Mexican population has a number of variations in certain genes that predispose ...

On the environmental trail of food pathogens

2 hours ago

Tracking one of the deadliest food contamination organisms through produce farms and natural environments alike, Cornell microbiologists are showing how to use big datasets to predict where the next outbreak could start.

Arriving now at gate 42: measles

14 hours ago

(HealthDay)—Traveling through the same U.S. airport gate, one infected passenger transmitted the measles virus to three others within a four-hour time span, illustrating just how easily the virus can spread, ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.