During the decade since the advent of highly active antiretroviral therapy (HAART), or 1996-2006, mortality among people living with HIV/AIDS (PLWHA) sharply decreased in the United States. So, too, did the percentages of PLWHA deaths attributable to AIDS-defining illnesses, just as there was a marked increase in the percentage of deaths attributable to heart, kidney, and liver disease.
These data from a US Centers for Disease Control and Prevention (CDC) review of trends in diseases reported on death certificates in the United States from 1996 to 2006 are published ahead of print in the Journal of the International Association of Physicians in AIDS Care (JIAPAC) published by SAGE.
Some specific findings about HIV deaths during the analysis period included:
- Deaths reported with HIV decreased from 35,340 to 13,750
- Deaths reported with AIDS-defining opportunistic infections decreased; and AIDS-defining cancers declined then had stable percentages after 2001
- Deaths reported with all other cancers increased from 2.7% to 7.3%
- Deaths reported with heart, kidney, and liver disease increased from 4.9% to 10.2%, 7.9% to 12.0%, and 5.8% to 13.0%, respectively
Explore further: Investigational HIV vaccine regimen shows encouraging results in non-human primates
More information: "Trends in Diseases Reported on U.S. Death Certificates that Mentioned HIV Infection, 1996-2006" is available free-of-charge for a limited time at jia.sagepub.com/content/early/2010/11/13/1545109710384505.full.pdf+html