Researchers identify PTSD measures for use in traumatic brain injury research

November 18, 2010

Five U.S. federal agencies recently cosponsored a set of expert work groups to formulate common data elements for research related to psychological adjustment and traumatic brain injury (TBI). Danny G. Kaloupek, PhD, associate professor of psychiatry and behavioral neuroscience at Boston University School of Medicine, chaired the work group on posttraumatic stress disorder (PTSD). Dr. Kaloupek's work at the National Center for PTSD at VA Boston Healthcare helped to guide identification of key PTSD-related characteristics and evidence-based measures that might be used in future research. The results have been published in the November 2010 issue of Archives of Physical Medicine and Rehabilitation.

PTSD has an estimated prevalence of approximately 8 percent among U.S. adults, with much higher rates in subpopulations that include combat exposed military personnel. Potential for co-occurrence of and TBI exists because the same types of violent and life-threatening experiences can cause both conditions. In addition, some of the ways that PTSD can affect functioning are similar to the effects of an increasingly recognized condition labeled mild TBI. For these reasons, PTSD-related measures are likely to be relevant for many studies focusing on TBI.

The work group members were experts from across the U.S. selected to provide a wide range of PTSD expertise. Individual members reviewed published evidence and held discussions to determine which characteristics and factors are most important to future research. Eight categories were identified and reviewed including exposure to traumatic stressors, factors that moderate life stress, PTSD symptoms, mental health history, and domains of functioning.

The work group agreed with several previous recommendations on PTSD measurement but also expanded the scope and updated coverage of the evidence. They described common trends such as greater prevalence of PTSD in women than men and elevated risk for PTSD among ethnic minorities in the U.S. They also noted that childhood adversity involving abuse or serious deprivation has increasingly been recognized as an element in the lives of many people who subsequently develop PTSD. The work group was careful to recognize that the scientific advantages associated with a common set of measures must be balanced with the benefits of innovation and emerging evidence. As Dr. Kaloupek comments, "the work group effort contributes to greater integration of knowledge regarding PTSD and TBI, with the ultimate aim of benefiting the lives of those who experience trauma."

Provided by Boston University Medical Center


Rank not rated yet
Relevant PhysicsForums posts
  • A question about drug tolerance
    createdMay 23, 2012
  • Poor nutrition leading to overeating?
    createdMay 23, 2012
  • Math and dyslexia?
    createdMay 21, 2012
  • portable metabolism meter?
    createdMay 21, 2012
  • Rare medical conditions on 20/20 tonight
    createdMay 18, 2012
  • "Good" Cholesterol in Doubt
    createdMay 17, 2012
  • More from Physics Forums - Medical Sciences

More news stories

Of mice and mental models: Neuroscientific implications of risk-optimized behavior in the mouse

(Medical Xpress) -- Regardless of an organism’s biological complexity, every encephalized animal continuously makes under-informed behavioral choices that can have serious consequences. Despite its ubiquity, ...

Medicine & Health / Neuroscience

created 16 hours ago | popularity not rated yet | comments 0 | with audio podcast feature

Skp2 activates cancer-promoting, glucose-processing Akt

HER2 and its epidermal growth factor receptor cousins mobilize a specialized protein to activate a major player in cancer development and sugar metabolism, scientists report in the May 25 issue of Cell.

Medicine & Health / Cancer

created 10 hours ago | popularity not rated yet | comments 0 | with audio podcast

Tongue analysis software uses ancient Chinese medicine to warn of disease

For 5,000 years, the Chinese have used a system of medicine based on the flow and balance of positive and negative energies in the body. In this system, the appearance of the tongue is one of the measures used to classify ...

Medicine & Health / Other

created 7 hours ago | popularity 1 / 5 (1) | comments 0 | with audio podcast

Cancer may require simpler genetic mutations than previously thought

Chromosomal deletions in DNA often involve just one of two gene copies inherited from either parent. But scientists haven't known how a deletion in one gene from one parent, called a "hemizygous" deletion, can contribute ...

Medicine & Health / Cancer

created 13 hours ago | popularity not rated yet | comments 0 | with audio podcast

First study to suggest that the immune system may protect against Alzheimer's changes in humans

Recent work in mice suggested that the immune system is involved in removing beta-amyloid, the main Alzheimer's-causing substance in the brain. Researchers have now shown for the first time that this may apply in humans.

Medicine & Health / Alzheimer's disease & dementia

created 14 hours ago | popularity 5 / 5 (3) | comments 0 | with audio podcast


Dragon arrives at space station in historic 1st (Update 2)

The privately bankrolled Dragon capsule made a historic arrival at the International Space Station on Friday, triumphantly captured by astronauts wielding a giant robot arm.

Landmark calculation clears the way to answering how matter is formed

(Phys.org) -- An international collaboration of scientists, including Thomas Blum, associate professor of physics, is reporting in landmark detail the decay process of a subatomic particle called a kaon – ...

High-speed method to aid search for solar energy storage catalysts

Eons ago, nature solved the problem of converting solar energy to fuels by inventing the process of photosynthesis.

It's in the genes: Research pinpoints how plants know when to flower

Scientists believe they've pinpointed the last crucial piece of the 80-year-old puzzle of how plants "know" when to flower.

Researchers solve structure of human protein critical for silencing genes

In a study published in the journal Cell on May 24, Cold Spring Harbor Laboratory (CSHL) scientists describe the three-dimensional atomic structure of a human protein bound to a piece of RNA that "guides" the pr ...

MIT researchers devise new means to synchronize a group of robots (w/ Video)

(Phys.org) -- For several years, roboticists have been working out ways to get a group of robots to perform synchronized activities as demonstrated most often in dance routines. It’s not just about trying ...