Key to tissue growth may be in anti-wrinkle cream

Nov 01, 2010

The first study to investigate the chemical structure of an advanced class of anti-wrinkle cream has shown that it could be used to promote wound healing and regenerative medicine.

Chemists at the University of Reading researched the nanostructure of a cosmetic ingredient used in high performance skincare creams - a peptide amphiphile (PA).

Many skincare products use to treat wrinkles. Skin is made up mostly of collagen; it is the foundation that gives your skin its support and thickness. Young people have lots of collagen and taut, smooth skin. In contrast, older people have much less collagen and thin, wrinkled skin.

Collagen is protein and is made up of long chains of strung together, like chains of linked building blocks. When it is broken down, short segments form, called peptides, and these act as a signal to tell your skin it is damaged and needs to make new collagen. The new research has revealed how the of the PA allows this to happen.

Professor Ian Hamley, from the Department of Chemistry, investigated the PA found in Matrixyl - an ingredient used in high end/state-of-the-art anti-ageing creams. He found that the PA contains a dense network of fine fibres that can act as an excellent scaffold for collagen to adhere to. This also has potential applications in tissue growth.

Professor Hamley said: "This the first report to our knowledge on a peptide amphiphile in current commercial use. Understanding the self-assembled structure is important in developing the next generation of collagen-stimulating peptides for applications not just for cosmetic skincare products but for and in ."

Explore further: New technique reveals immune cell motion through variety of tissues

More information: The paper, Fibrillar Superstructure from Extended Nanotapes Formed by a Collagen-Stimulating Peptide by Valeria Castelletto, et al. is published in Chemical Communications, DOI:10.1039/c0cc03793a

Provided by University of Reading

5 /5 (5 votes)

Related Stories

Another new wrinkle in treating skin aging

Jun 05, 2008

Topical applications of a naturally occurring fat molecule have the potential to slow down skin aging, whether through natural causes or damage, researchers report.

Scientists create super-strong collagen

Jan 12, 2010

(PhysOrg.com) -- A team of University of Wisconsin-Madison researchers has created the strongest form of collagen known to science, a stable alternative to human collagen that could one day be used to treat arthritis and ...

Sun-damaged skin does not improve with estrogen treatments

Sep 15, 2008

Treating the skin with estrogen can stimulate collagen production—which improves the appearance of the skin—in areas not typically exposed to the sun, according to new research from the University of Michigan Health System.

Research reveals structure and behavior of collagen

Feb 26, 2008

The structure and behavior of one of the most common proteins in our bodies has been resolved at a level of detail never before seen, thanks to new research performed at the Advanced Photon Source (APS) at the U.S. Department ...

Recommended for you

'Global positioning' for molecules

Dec 19, 2014

In everyday life, the global positioning system (GPS) can be employed to reliably determine the momentary location of one en route to the desired destination. Scientists from the Institute of Physical and ...

Cells build 'cupboards' to store metals

Dec 17, 2014

Lawrence Livermore researchers in conjunction with collaborators at University of California (link is external), Los Angeles have found that some cells build intracellular compartments that allow the cell ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.