Adding monounsaturated fats to a low-cholesterol diet can further improve levels

Nov 01, 2010

The addition of monounsaturated fat (MUFA) to a cholesterol-lowering dietary portfolio in patients with mild to moderate elevated cholesterol levels increased HDL by 12.5% and lowered LDL levels by 35%, found a study published in CMAJ (Canadian Medical Association Journal).

Low HDL-C levels and high LDL-C levels are a risk factor for cardiovascular disease. The addition of dietary monounsaturated fat, common in the , is a current approach to raising HDL-C levels.

The study included 24 patients (17 men and 7 postmenopausal women) who completed a very low saturated fat diet before being randomly assigned to either a high-MUFA diet or a low- MUFA diet. Both groups of patients were assigned to a specific vegetarian diet which included oats, barley, psyllium, eggplant, okra, soy, almonds and a plant sterol enriched margarine. In the high-MUFA group, the researchers substituted 13% of calories from carbohydrates with a high-MUFA sunflower oil, with the option of a partial exchange with avocado oil.

They found significant reductions in blood cholesterol levels over the two month study period for participants.

"The replacement of 13% of total calories from carbohydrate by monounsaturated fats in the dietary portfolio resulted in a 12.5% greater increase in HDL-C over the four weeks, while not altering the substantial LDL-C reduction," writes Dr. David Jenkins, and Risk Factor Modification Centre, St. Michael's Hospital, Toronto, with coauthors.

Other strategies to raise HDL-C include exercise and moderate consumption of alcohol as well as weight loss and .

"The addition of MUFA increased HDL-C and therefore may further enhance the cardioprotective effect of the cholesterol-lowering dietary portfolio without diminishing its cholesterol-lowering effect," state the authors.

However, they state that the long-term effect on diets that are self-directed by patients needs to be determined as do cardiovascular outcomes.

Explore further: Is UK shale gas extraction posing a risk to public health?

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Obama: 8 million signed up for health care (Update)

4 hours ago

President Barack Obama said Thursday 8 million Americans have signed up for health care through new insurance exchanges, besting expectations and offering new hope to Democrats who are defending the law ahead ...

User comments : 0

More news stories

Turning off depression in the brain

Scientists have traced vulnerability to depression-like behaviors in mice to out-of-balance electrical activity inside neurons of the brain's reward circuit and experimentally reversed it – but there's ...

Researchers discover target for treating dengue fever

Two recent papers by a University of Colorado School of Medicine researcher and colleagues may help scientists develop treatments or vaccines for Dengue fever, West Nile virus, Yellow fever, Japanese encephalitis and other ...

Our brains are hardwired for language

A groundbreaking study published in PLOS ONE by Prof. Iris Berent of Northeastern University and researchers at Harvard Medical School shows the brains of individual speakers are sensitive to language univer ...

Study recalculates costs of combination vaccines

One of the most popular vaccine brands for children may not be the most cost-effective choice. And doctors may be overlooking some cost factors when choosing vaccines, driving the market toward what is actually a more expensive ...

Better thermal-imaging lens from waste sulfur

Sulfur left over from refining fossil fuels can be transformed into cheap, lightweight, plastic lenses for infrared devices, including night-vision goggles, a University of Arizona-led international team ...

Hackathon team's GoogolPlex gives Siri extra powers

(Phys.org) —Four freshmen at the University of Pennsylvania have taken Apple's personal assistant Siri to behave as a graduate-level executive assistant which, when asked, is capable of adjusting the temperature ...