New polio vaccine raises hope for eradication: study

Oct 26, 2010

A new polio vaccine offers superior immunisation and is raising hopes of a total eradication of the disease, according to a study published on Tuesday by British medical journal The Lancet.

There are three types of the virus, and while type 2 has been almost entirely eradicated since mass vaccinations began in 1988, types 1 and 3 remain a global health threat.

The new bivalent vaccine targets types 1 and 3, and was shown to be significantly more effective than the common trivalent vaccine in a 2008 trial in India.

In the trial, conducted by experts from the World Health Organisation and India, 830 new-born babies at three medical centres were give either existing vaccines or the new bivalent vaccine.

The new vaccine presented immunity against type 1 polio in 90 percent of babies, compared with 63 percent from the trivalent vaccine. The new vaccine presented 74 percent immunity for type 3, against 52 percent with the trivalent vaccine. A monovalent vaccine for type 3 led to 84 percent immunity.

Polio is a threat in four countries, namely India, Afghanistan, Pakistan and Nigeria, compared to 125 countries in 1988. There were 1,606 cases of polio last year, down from about 350,000 in 1988.

The new is already being widely used in India, and the number of polio cases was down to 32 so far this year, from 260 last year, the journal said, quoting researchers Nigel Crawford and Jim Buttery from the Murdoch Children's Research Institute in Melbourne, Australia.

The researchers warned that progress in polio immunisation was being undermined by a lack of funds, and called for a "final, concerted effort" to stamp it out.

Explore further: Risk of antibiotic overuse in aged care settings

add to favorites email to friend print save as pdf

Related Stories

Polio eradication hinges on four countries

Oct 13, 2006

Successfully global eradication of polio depends four countries' efforts to vaccinate children, the Swiss-based Advisory Committee on Polio Eradication said.

Polio outbreak in Tajikistan is cause for alarm

Jun 23, 2010

The rapidly growing polio outbreak in Tajikistan raises serious concerns that the disease could spread to other regions in the world, states an editorial in CMAJ (Canadian Medical Association Journal). It is imperative th ...

Polio's eradication still uncertain

Dec 26, 2007

Efforts to wipe out polio have stalled in recent years and eradication of the crippling disease remains a question mark, U.S. and world experts say.

Polio surge in Nigeria after vaccine virus mutates

Aug 14, 2009

(AP) -- Polio, the dreaded paralyzing disease stamped out in the industrialized world, is spreading in Nigeria. And health officials say in some cases, it's caused by the vaccine used to fight it.

Recommended for you

Supermaterial gives rejected drugs a new chance

7 hours ago

More than 80 percent of all drug candidates in the pharma R&D suffer from poor solubility and are therefore rejected early in the drug discovery process. Now Uppsala University researchers show that the new ...

Risk of antibiotic overuse in aged care settings

Jul 21, 2014

Antibiotics are being overused in residential aged care facilities (RACFs), and more integrated efforts to improve antibiotic prescribing practices need to be introduced, researchers say. 

Ruconest approved for rare genetic disease

Jul 17, 2014

(HealthDay)—Ruconest has been approved by the U.S. Food and Drug Administration to treat hereditary angioedema, a genetic disease that leads to sudden and potentially fatal swelling of the hands, feet, limbs, face, intestinal ...

NIH system to monitor emerging drug trends

Jul 17, 2014

An innovative National Drug Early Warning System (NDEWS) is being developed to monitor emerging trends that will help health experts respond quickly to potential outbreaks of illicit drugs such as heroin and to identify increased ...

User comments : 0