Questioning the safety of certain 'healthful' plant-based antioxidants

September 8, 2010

Scientists are calling for more research on the possibility that some supposedly healthful plant-based antioxidants — including those renowned for their apparent ability to prevent cancer — may actually aggravate or even cause cancer in some individuals. Their recommendation follows a study in which two such antioxidants — quercetin and ferulic acid — appeared to aggravate kidney cancer in severely diabetic laboratory rats.

The study appears in ACS' bi-weekly Journal of Agricultural and Food Chemistry.

Kuan-Chou Chen, Robert Peng, and colleagues note that , fruits, and other plant-based foods are rich in antioxidants that appear to fight cancer, diabetes, , and other disorders. Among those antioxidants is quercetin, especially abundant in onions and black tea, and ferulic acid, found in corn, tomatoes, and rice bran. Both also are ingredients in certain herbal remedies and dietary supplements. But questions remain about the safety and effectiveness of some antioxidants, with research suggesting that quercetin could contribute to the development of cancer, the scientists note.

They found that diabetic laboratory rats fed either quercetin or ferulic acid developed more advanced forms of , and concluded the two antioxidants appear to aggravate or possibly cause kidney cancer. "Some researchers believe that quercetin should not be used by healthy people for prevention until it can be shown that quercetin does not itself cause cancer," the report states. "In this study we report that quercetin aggravated, at least, if not directly caused, kidney cancer in rats," it adds, suggesting that health agencies like the U. S. should reevaluate the safety of plant-based antioxidants.

Explore further: Naturally-occurring apple compounds reduce risk of pancreatic cancer

More information: "Quercetin and Ferulic Acid Aggravate Renal Carcinoma in Long-Term Diabetic Victims" pubs.acs.org/stoken/presspac/presspac/full/10.1021/jf101580j

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nonknown101
1 / 5 (1) Sep 19, 2010
these forms of testing chemicals are complete nonsense!
there arte many organic chemicals that cause no harm to humans but cause disease in other mammals.
the use of rodents in studies is a practice that should be outlawed, the results are always flawed.
the reason is simple, rodents can not vomit, they can not cough up phlegm, the fact that a rat can't vomit is how we are able to poison rats with cyanide, if a lethal dose of cyanide is swallowed by a human it acts as an emetic and a purgative, some thing that doesn't happen in a rats guts!!
what this means is that these scientist can give the rats doses of these chemicals in doses that no other form of life could keep in their belly, and this doesn't even cover the different enzymes in rodentia bodies as compared to humans that could cause different by products that would never be found in the human body.
this form of testing is not science, it is a way to get grant money and nothing else!!

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