New model to measure disease burden of postmenopausal osteoporosis

September 8, 2010

An article just published in the scientific journal Osteoporosis International introduces a validated new model that can be used to describe the current and future burden of postmenopausal osteoporosis in different national settings.

The model, published by researchers from the UK on behalf of the International Foundation's Committee of Scientific Advisors, was developed and validated using Swedish data. It can be used to forecast the incidence and prevalence of fractures not only by age and calendar year, but also by BMD category. It provides a high degree of accuracy, as the predictions of fracture rates for all fracture sites were within a 5% margin of error compared with published data when averaged across ages.

The incidence of osteoporotic fractures increases markedly with age and, given the rapidly ageing populations in many countries of the world, there is a real need to predict the future burden of fractures. For example in Europe, where the proportion of the population aged 65 or over will increase from 17% in 2008 to 30% in 2060, a serious increase in the number of osteoporotic fractures is expected. Even more marked increases are projected in other regions of the world, particularly in Asia where a 7.6-fold increase in elderly people is predicted between 2000 and 2050.

The new model provides a potentially powerful tool to inform decision making. Early diagnosis and effective fracture prevention strategies could translate into huge cost savings for health care systems around the world.

Explore further: Osteoporosis screening and treatment may be cost-effective for selected older men

More information: Development and validation of a disease model for postmenopausal osteoporosis. A. Gauthier, J.A. Kanis, M. Martin, J. Compston, F. Borgström, C. Cooper, E. McCloskey, On behalf of the IOF Committee of Scientific Advisors. DOI: 10.1007/s00198-010-1358-3

Related Stories

Osteoporosis care at risk in the United States

November 12, 2008

The reimbursement cuts run contrary to existing federal initiatives already in place to increase fracture prevention efforts and improve the prevention, diagnosis and treatment of osteoporosis.

Recommended for you

How the finch changes its tune

August 3, 2015

Like top musicians, songbirds train from a young age to weed out errors and trim variability from their songs, ultimately becoming consistent and reliable performers. But as with human musicians, even the best are not machines. ...

Machine Translates Thoughts into Speech in Real Time

December 21, 2009

( -- By implanting an electrode into the brain of a person with locked-in syndrome, scientists have demonstrated how to wirelessly transmit neural signals to a speech synthesizer. The "thought-to-speech" process ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.